Isochrysis Extract for Stable Self-Tanning

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Solution Overview

Problem

Current self-tanning products using dihydroxyacetone and erythrulose induce oxidative stress, generate free radicals, and lack natural sun protection, while biologically acting tanners like acetyl tyrosine require medical indications and have stability issues in cosmetic formulations.

Innovation Solution

A supercritical fluid CO2 extract of Isochrysis sp., particularly Tahitian Isochrysis, with controlled carotenoid, chlorophyll, and fatty acid content, which increases cutaneous melanin, reduces oxidative stress, and improves skin and hair hydration without intense color or odor, allowing for stable and easy formulation in cosmetic products.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If dihydroxyacetone is used as a self-tanning agent, then skin browning is achieved, but oxidative stress and free radical generation occur

Engineering Contradiction:
Improveskin browning capabilityVSAvoidoxidative stress
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and isolates specific antioxidants (vitamin E, carotenoids, polyphenols) from plant sources to create a composition that counteracts the oxidative stress caused by dihydroxyacetone, while maintaining the desired skin browning effect

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent converts the harmful oxidative stress and free radicals generated by dihydroxyacetone into beneficial effects by adding antioxidants that neutralize these harmful byproducts, transforming a harmful chemical reaction into a beneficial protective mechanism

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Ease of manufacture

If dihydroxyacetone is used for self-tanning, then skin browning is achieved, but the tan lacks natural sun protection

Engineering Contradiction:
Improveskin browning capabilityVSAvoidsun protection
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent creates a composite formulation combining dihydroxyacetone (for browning) with natural antioxidants from plant sources (for protection), resulting in a multi-functional product that provides both cosmetic tanning and protective benefits

Inventive Principle:
Principle #40Composite materials

3Quantity of substance

If carotene preparations are consumed to increase skin carotene levels, then skin turns orange-yellow, but the tone does not resemble natural tan

Engineering Contradiction:
Improveskin carotene levelsVSAvoidskin tone appearance
Core Design Contradiction:
Quantity of substanceVSShape

Solution Approach 1:

The patent applies antioxidants locally to the skin surface through topical application, allowing the active ingredients to work directly at the site of dihydroxyacetone action without altering the overall skin tone to an unnatural orange-yellow hue

Inventive Principle:
Principle #3Local quality

4Ease of manufacture

If self-tanning products are used to achieve skin browning, then tan is obtained, but formulation stability is poor

Engineering Contradiction:
Improveskin browning capabilityVSAvoidformulation stability
Core Design Contradiction:
Ease of manufactureVSStability of the object's composition

Solution Approach 1:

The plant-derived antioxidants serve as intermediary substances that stabilize the formulation by neutralizing free radicals and preventing degradation of the dihydroxyacetone and other formulation components, thereby improving overall product stability

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The extract provides a natural, stable, and effective means to enhance skin and hair pigmentation, reduce oxidative stress, and improve hydration, offering a faster and longer-lasting tan with improved formulation properties compared to existing products.

Implementation Method 1

a supercritical fluid CO2 extract of Isochrysis sp. and/or Tisochrysis sp. for increasing pigmentation of human skin

Methodology Applied
Scientific EffectMelanogenesis:

Implementation Method 2

the extract according to the invention significantly reduces oxidative stress induced changes

Methodology Applied
Scientific EffectOxidative stress reduction: Oxidation

Data Source

PatentUS20240130957A1Extracts of isochrysis species/tisochrysis species
Publication Date: 2024.04.25 SYMRISE GMBH & CO KG
  • US20240130957A1 patent drawing
  • US20240130957A1 patent drawing
  • US20240130957A1 patent drawing

AI summary

Suggested is a supercritical fluid CO2 extract of Isochrysis sp. and/or Tisochrysis sp. comprising: a) not more than 1.5% b.w. of carotenoids; b) not more than 2.0% b.w. of chlorophylls; and c) at least 15% b.w. of free fatty acids, each weight percentage amount based on the total weight of the extract, wherein the extract has a gardner color value of not more than 9 at an extract concentration of 0.018% in oil.