Isofucosterol in Pollen-Free Bee Feed for Brood Production

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Solution Overview

Problem

Current artificial diets for bees are incomplete, leading to rapid decline in brood production after 3-4 cycles, as they lack essential nutrients, and commercially available feeds do not contain pollen due to its limited availability, high cost, and contamination issues.

Innovation Solution

Incorporating isofucosterol and a combination of sterols such as cholesterol, 24-Methylenecholesterol, campesterol, beta-sitosterol, and stigmasterol into a pollen-free diet to provide the necessary nutrients for sustained brood production and colony development.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pollen is used as bee feed, then bees obtain essential nutrients including sterols, but pollen is costly, hard to keep fresh, and can carry pests and diseases

Engineering Contradiction:
Improvebee nutrition qualityVSAvoidpests, diseases, and pesticides contamination
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the essential nutritional components (sterols including isofucosterol, campesterol, beta-sitosterol, and cholesterol) from natural pollen and formulates them into an artificial diet. This separation allows bees to receive necessary nutrients without exposure to contaminants present in natural pollen collections

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent modifies the sterol composition parameters by adding isofucosterol at specific concentrations (0.01-2% of diet weight) to artificial diets, changing the nutritional profile to match or exceed natural pollen quality while avoiding contamination issues

Inventive Principle:
Principle #35Parameter changes

2Reliability

If pollen collection is increased to meet bee nutritional needs, then bee colony health improves, but costs increase and resource availability decreases

Engineering Contradiction:
Improvebee colony healthVSAvoidpollen availability
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent creates an artificial copy of natural pollen's nutritional profile by synthesizing a diet containing specific sterols (isofucosterol, campesterol, beta-sitosterol, cholesterol) in appropriate concentrations, making natural pollen obsolete as a required resource

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The artificial diet formulation serves multiple functions: it provides complete sterol nutrition, eliminates contamination risks, reduces costs, and can be stored indefinitely, replacing the multiple roles natural pollen plays in bee nutrition

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Ease of manufacture

If current artificial diets without isofucosterol are used, then bees are fed a pollen-free diet, but brood production declines rapidly after 3-4 cycles

Engineering Contradiction:
Improveartificial diet productionVSAvoidbrood production
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent identifies and corrects the nutritional deficiency by adding isofucosterol at optimized concentrations (0.01-2% of diet weight) to the artificial diet formulation, changing the sterol composition parameters to support sustained brood production

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent incorporates isofucosterol and other essential sterols into the artificial diet formulation from the beginning, preventing nutritional deficiencies before they cause brood production decline, rather than correcting the problem after it manifests

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20240315283A1Isofucosterol a key nutrient for phytosterol eating animals such as pollen eating and algae-eating and plankton eating organisms
Publication Date: 2024.09.26 APIX BIOSCIENCES
  • US20240315283A1 patent drawing
  • US20240315283A1 patent drawing
  • US20240315283A1 patent drawing

AI summary

Provided is a method for feeding invertebrates or aquaculture organisms comprising: #providing a non-pollen composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and #administering the non-pollen composition to invertebrates.