Isothiazoline Compounds for Resistant Invertebrate Pest Control
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current pesticidal agents face challenges due to the development of resistance by invertebrate pests, particularly arthropods and nematodes, necessitating the need for new compounds with broad-spectrum insecticidal activity.
Innovation Solution
Isothiazoline compounds with specific heterocyclic radicals and substituents, including their stereoisomers and salts, are developed to effectively combat a wide range of invertebrate pests.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing pesticidal agents are used, then initial pesticidal activity is achieved, but resistance development by invertebrate pests occurs over time
Solution Approach 1:
The patent applies parameter changes by developing novel chemical compounds with modified molecular structures (isothiazoline core with specific heterocyclic substituents). This changes the chemical parameters of the pesticidal agent, creating new compounds that pests have not developed resistance against, thereby restoring and maintaining effective pesticidal activity against resistant pest populations
Solution Approach 2:
The patent employs composite materials by creating complex molecular structures that combine an isothiazoline core with various heterocyclic rings and substituent groups. These composite chemical structures provide enhanced pesticidal properties and broad-spectrum activity against multiple pest types, addressing resistance issues through structural complexity and diversity
2Adaptability or versatility
If broad-spectrum pesticidal activity is pursued, then activity against multiple pest types is achieved, but compound complexity increases
Solution Approach 1:
The patent applies universality by designing isothiazoline compounds with heterocyclic substituents that provide broad-spectrum pesticidal activity against multiple pest types including insects, mites, and nematodes. The core isothiazoline structure with variable heterocyclic groups enables a single compound class to perform multiple pesticidal functions across different target organisms
Solution Approach 2:
The patent uses segmentation by dividing the pesticidal compound into distinct functional modules: a core isothiazoline structure and separate heterocyclic substituent groups. This modular approach allows systematic variation of substituents to optimize activity against different pest types while maintaining the fundamental pesticidal mechanism, thereby managing complexity through structured design
Data Source
AI summary
The present invention relates to thiophene- or furan-substituted isothiazoline compounds of formula Iwherein the variables are as defined in the claims and description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.