Isotropic MRI Imaging via Multi-Plane Data Fusion

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Solution Overview

Problem

Current 3D MRI scanning techniques suffer from low resolution in one dimension, leading to limitations in 3D image analysis and visualization, increased partial volume effects, and missed boundaries due to scanning resolution and orientation issues.

Innovation Solution

The method involves performing multiple MRI scans in different planes and merging them to create an isotropic or near-isotropic data volume, where gray values are interpolated to achieve higher resolution in all three dimensions, reducing partial volume effects and improving tissue segmentation and analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional 3D MRI scanning techniques are used, then the imaging speed and coverage are improved, but the resolution in one dimension deteriorates leading to partial volume effects and missed boundaries

Engineering Contradiction:
Improveimaging speedVSAvoidresolution
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent acquires MRI data in multiple orientations (e.g., axial, coronal, sagittal planes) and combines them to create an isotropic 3D volume. This multi-dimensional approach ensures high resolution in all three spatial dimensions by leveraging the strength of each orientation, eliminating the need to compromise resolution in any single dimension for the sake of imaging speed.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Area of stationary object

If conventional 3D MRI scanning techniques are used, then the imaging coverage is improved, but the manufacturing precision of isotropic image data deteriorates

Engineering Contradiction:
Improveimaging coverageVSAvoidisotropic image data quality
Core Design Contradiction:
Area of stationary objectVSManufacturing precision

Solution Approach 1:

The patent merges multiple 2D MRI scans taken in different planes and orientations to construct a single isotropic 3D volume. By combining data from multiple acquisitions with different coverage areas and orientations, the method achieves both comprehensive imaging coverage and uniform isotropic resolution throughout the entire volume, avoiding the trade-off between coverage and precision.

Inventive Principle:
Principle #5Merging (Combining)

3Productivity

If conventional 3D MRI scanning techniques are used, then the scanning efficiency is improved, but the detection precision of boundaries and structures deteriorates

Engineering Contradiction:
Improvescanning efficiencyVSAvoidboundary detection precision
Core Design Contradiction:
ProductivityVSDifficulty of detecting and measuring

Solution Approach 1:

By acquiring and combining data from multiple orientations, the patent creates isotropic voxels that provide equal resolution in all directions. This enables accurate boundary detection and structural measurement in any plane through the 3D volume, eliminating the directional resolution limitations of conventional anisotropic scanning while maintaining scanning efficiency.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy of 3D image analysis and tissue segmentation by providing high-resolution images in all directions, reducing partial volume effects and improving the detection of boundaries, thereby facilitating more precise diagnostic and treatment strategies.

Implementation Method 1

Via radio frequency (RF) magnetic field (B1) excitation and manipulations, selected magnetic dipoles in the subject that are otherwise aligned with the main magnetic field are tipped to excite magnetic resonance. The resonance is typically manipulated to induce detectable magnetic resonance echoes from a selected region of the subject.

Methodology Applied
Scientific EffectMagnetic resonance:

Implementation Method 2

In imaging, the echoes are spatially encoded via magnetic gradients set up in the main magnetic field.

Methodology Applied
Scientific EffectMagnetic field encoding: Magnetic Field

Data Source

PatentUS7634119B2Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging
Publication Date: 2009.12.15 CONFORMIS INC
  • US7634119B2 patent drawing
  • US7634119B2 patent drawing
  • US7634119B2 patent drawing

AI summary

In accordance with the present invention there is provided methods for generating an isotropic or near-isotropic three-dimensional images from two-dimensional images. In accordance with the present invention the method includes, obtaining a first image of a body part in a first plane, wherein the first image generates a first image data volume; obtaining a second image of the body part in a second plane, wherein the second image generates a second image data volume; and combining the first and second image data volumes to form a resultant image data volume, wherein the resultant image data volume is isotropic or near-isotropic.