Isoxazolin Phenyl Thiocarbamates for Low-Rate Selective Weed Control
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing herbicides suffer from insufficient herbicidal activity, particularly at low application rates, unsatisfactory selectivity, and high toxicity for humans and animals, as well as low compatibility with crop plants.
Innovation Solution
Development of phenylthiocarbamate compounds with specific substituents on the isoxazolin-substituted phenyl ring, including agriculturally acceptable salts and stereoisomers, which provide high herbicidal activity, low toxicity, and high compatibility with crop plants.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If existing herbicidal phenylthionocarbamates are used, then herbicidal activity is achieved, but activity is insufficient at low application rates
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of phenylthionocarbamate molecules, specifically introducing isoxazolin-substituted phenyl rings with various substituents (R1-R7 groups). This structural parameter modification enhances the herbicidal activity per unit mass, allowing effective control at lower application rates while maintaining reliability against target weeds.
Solution Approach 2:
The invention creates composite herbicidal compounds by combining multiple functional groups within the molecular structure - the isoxazolin ring, phenyl ring, and various substituent groups work synergistically to produce enhanced herbicidal activity that exceeds the sum of individual components, achieving high efficacy at low application rates.
2Adaptability or versatility
If existing herbicidal compounds are used, then broad spectrum activity is achieved, but selectivity for crop plants is unsatisfactory
Solution Approach 1:
The patent applies local quality by introducing specific substituent groups (R1-R7) at particular positions on the isoxazolin-substituted phenyl ring. These localized structural modifications create compounds that selectively interact with weed biochemical pathways while sparing crop plants, achieving both broad spectrum activity and crop safety through precise molecular design.
Solution Approach 2:
By systematically varying substituent parameters (different R groups at positions R1-R7), the patent optimizes the balance between broad spectrum herbicidal activity and selectivity for crop plants. Specific parameter combinations enhance affinity for weed targets while reducing phytotoxicity to crops.
3Reliability
If existing herbicidal compounds are used, then herbicidal effect is achieved, but toxicity for humans and animals is high
Solution Approach 1:
The patent modifies molecular parameters by introducing isoxazolin rings and specific substituent groups that enhance herbicidal activity through improved target binding affinity. These structural changes increase potency per unit mass, thereby reducing the total amount of active substance required and consequently lowering toxicity exposure for humans and animals while maintaining reliable herbicidal control.
4Reliability
If existing herbicidal compounds are used, then herbicidal activity is achieved, but compatibility with crop plants is low
Solution Approach 1:
The patent applies local quality through specific substituent placement on the isoxazolin-substituted phenyl ring structure. Certain R groups at specific positions (R2-R7) are designed to reduce non-selective phytotoxicity while preserving herbicidal activity, thereby improving compatibility with crop plants through localized molecular optimization.
Data Source
AI summary
The present invention relates to thiocarbamates carrying an isoxazolin-substituted phenyl ring of the formula (I) wherein the variables are as defined in the claims and the description, and to compositions comprising the same. The invention also relates to the use of said thiocarbamates or composiions containing the same for controlling/combatting undesired vegetation and to methods of controlling/combatting undesired vegetation comprising applying said thiocarbamates or compositions containing the same.