Isoxazoline Oxime Formate Herbicide Selectivity
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Solution Overview
Problem
Current herbicides lack satisfactory herbicidal properties against harmful plants and crop selectivity, leading to issues like weed resistance and environmental concerns, necessitating the development of new compounds with high efficacy, safety, and economic viability.
Innovation Solution
The development of an isoxazoline oxime formate compound with a specific chemical structure, shown in general formula I, which exhibits excellent herbicidal activity against grassy and broadleaf weeds at low application rates while maintaining high selectivity to crops.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If known herbicides (aryl-4-thiotriazine, isoxazoline-containing uracil compound) are used, then weed control function is provided, but herbicidal properties against harmful plants and selectivity to crops are not satisfactory
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of known herbicides through systematic variation of substituents (R1-R7, Y, Z, Q, X1-X5) in the general formula I. This creates a series of derivatives with different biological activities, allowing optimization of both herbicidal efficacy against various harmful plants and selectivity to crops. The structural parameters are changed to achieve superior performance compared to parent compounds.
Solution Approach 2:
The patent employs composite materials by combining multiple functional groups and structural motifs within the general formula I framework. The molecule integrates heterocyclic rings, oxime formate groups, and various substituent patterns that work synergistically to enhance herbicidal activity while maintaining crop safety. This composite structural approach produces compounds with improved properties compared to simpler known herbicides.
2Reliability
If application rate is increased to improve weed control, then herbicidal activity increases, but crop safety and economic viability deteriorate
Solution Approach 1:
The patent achieves high weed control efficacy at low application rates through parameter changes in the molecular structure. The optimized derivatives of general formula I exhibit enhanced biological activity, allowing effective herbicidal action at reduced concentrations. This reduces the quantity of substance required while maintaining or improving weed control performance.
3Reliability
If existing herbicides are used continuously, then weed control is maintained, but weed resistance develops and environmental concerns increase
Solution Approach 1:
The patent applies segmentation by dividing the herbicidal function into multiple distinct chemical structures (various derivatives of general formula I with different substituent patterns). This provides a diversified approach to weed control, reducing the risk of resistance development compared to continuous use of a single herbicide. The segmented strategy offers multiple modes of action.
Solution Approach 2:
The patent uses parameter changes to create chemically distinct herbicides with varying physical and biological properties. This diversification reduces environmental persistence and toxicity concerns while maintaining effective weed control. The modified structural parameters result in compounds with improved safety profiles compared to existing herbicides.
Data Source
AI summary
The present invention belongs to the technical field of pesticides, and specifically relates to an isoxazoline oxime formate compound, a preparation method therefor, and a herbicidal composition and a use thereof. The isoxazoline oxime formate compound is shown in general formula I.Wherein, Y represents halogen, haloalkyl, cyano, nitro or amino; Z represents hydrogen, halogen or hydroxyl; Q representsM represents CH or N; X1, X2 and X3 each independently represent hydrogen, etc.; X4 and X5 each independently represent hydrogen, halogen, cyano or nitro, etc. The compound also has an excellent herbicidal activity against grassy weeds, broadleaf weeds, etc. at a low application rate, and has a high selectivity to crops.