IV Compounding Workflow Verification for Accurate Medication Mixing

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Solution Overview

Problem

The preparation of intravenous medications in pharmacies requires meticulous attention to correct proportions and contamination-free compounding, often involving non-registered workers or robotic machines, necessitating robust protocols and documentation, but existing systems lack efficient methods for automating and verifying the compounding process.

Innovation Solution

A system and method for pharmaceutical compounding that utilizes a user interface to select workflow types, device types, and options, automatically constructing compounding protocols, and transmitting them to compounding devices, with verification techniques like weight and photographic checks, ensuring accuracy and reducing human error.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual compounding by non-registered workers is used, then labor flexibility is improved, but compounding accuracy and reliability deteriorate

Engineering Contradiction:
Improvelabor flexibilityVSAvoidcompounding accuracy
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The compounding device performs self-verification of compounding parameters through automated sensors and processors that independently check weight, volume, and mixing parameters without requiring human expertise for verification

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

Manual compounding operations are replaced with automated mechanical and electronic systems that precisely control and verify compounding parameters, substituting human judgment with instrumented measurement and control systems

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If detailed protocols are developed for each medication, then compounding precision is improved, but system complexity worsens

Engineering Contradiction:
Improvecompounding precisionVSAvoidprotocol management complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

A single compounding device platform performs multiple functions across different medication types by loading different protocol sets, eliminating the need for separate dedicated equipment for each medication while maintaining precision through protocol-specific parameters

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

Compounding protocols are pre-configured and stored in the system memory with all parameters defined in advance, allowing the device to automatically retrieve and execute the appropriate protocol without requiring complex real-time decision-making or manual protocol assembly

Inventive Principle:
Principle #10Preliminary action

3Productivity

If robotic compounding is implemented, then productivity is improved, but ease of operation worsens

Engineering Contradiction:
Improvecompounding throughputVSAvoidsystem operation simplicity
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

A user interface acts as an intermediary between the operator and the robotic compounding system, providing simplified controls and display that mask the complexity of the underlying automated mechanisms while enabling efficient operation

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS12580059B2IV compounding systems and methods
Publication Date: 2026.03.17 OMNICELL INC
  • US12580059B2 patent drawing
  • US12580059B2 patent drawing
  • US12580059B2 patent drawing

AI summary

Systems and methods of compounding of medication include a user interface that enables efficient design of compounding workflows and protocols. A user can select a workflow type from a number of workflow types differentiated at least in part by the vehicle in which a compounded pharmaceutical is to be delivered, and the user may also specify a compounding device. Options are presented and the steps of a workflow in accordance with the workflow type and options is displayed and updated in real time as options are selected. A protocol can be constructed by inserting information into the workflow based on a specification of a particular pharmaceutical to be compounded.