Automated IV Infusion Compounding With Integrated Volume Control
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Solution Overview
Problem
Existing IV infusion preparation and delivery systems are complex, generate significant waste, and pose risks of contamination and error due to multiple components and manual handling, particularly in at-home settings.
Innovation Solution
A consolidated, automated IV infusion device with a compounding assembly and integrated valves, actuators, and volume adjustors to streamline the preparation process, reducing manual steps and integrating automation for precise fluid control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If multiple separate components and manual handling are used for IV infusion preparation, then flexibility in preparation can be maintained, but device complexity increases and contamination risks increase
Solution Approach 1:
The patent combines multiple separate components (reconstitution apparatus, infusion apparatus, volume adjustors, valves) into a single integrated device housing. This merging eliminates the need for multiple separate manual operations and reduces the risk of contamination by minimizing the number of times components need to be opened or connected, while maintaining ease of operation through automated coordination of all components.
Solution Approach 2:
The integrated device performs multiple functions within a single system: it can reconstitute drugs, control volumes precisely, manage fluid flow through valves, and transfer solutions to infusion bags. This multi-functionality consolidates what would traditionally require multiple separate devices or manual steps into one unified system, reducing complexity while maintaining operational flexibility.
2Adaptability or versatility
If multiple separate components and manual handling are used for IV infusion preparation, then adaptability to different preparations can be maintained, but contamination risks increase
Solution Approach 1:
By merging all preparation and delivery components into a single sealed device, the system maintains adaptability for different IV preparations while minimizing contamination risk. The integrated design allows different drugs and formulations to be prepared using the same closed system, eliminating exposure to external contaminants during manual transfers and component connections.
Solution Approach 2:
The patent introduces controlled access points (such as sealed ports and valve mechanisms) that act as intermediaries between the internal preparation chambers and the external environment. These controlled interfaces allow adaptability for different preparations while maintaining a protected internal environment that prevents contamination during the preparation and transfer processes.
3Ease of operation
If manual handling and multiple components are used, then operational flexibility is maintained, but productivity decreases
Solution Approach 1:
The integrated device performs self-service automation where the system automatically coordinates the sequence of operations including drug reconstitution, volume adjustment, and solution transfer. The automated valves and pumps eliminate manual handling steps, maintaining operational flexibility for different preparations while dramatically improving productivity by eliminating time-consuming manual operations.
Solution Approach 2:
The device is pre-configured with automated sequencing and pre-positioned components that execute preparation steps in the correct order without manual intervention. Volume adjustors and valves are pre-programmed to control fluid flow automatically, allowing the system to maintain operational flexibility while preparing infusions rapidly through predetermined automated actions.
4Manufacturing precision
If automated volume control mechanisms are added, then manufacturing precision of fluid volumes is improved, but device complexity increases
Solution Approach 1:
The patent integrates volume control mechanisms directly into the existing apparatus structure, merging the volume adjustors with the reconstitution and infusion chambers. This integration achieves precise volume control through mechanical linkages and controlled valve positions without adding separate complex control systems, maintaining manufacturing precision while minimizing the increase in device complexity.
Solution Approach 2:
The patent replaces manual volume adjustment mechanisms with automated mechanical or electromechanical control systems. The volume adjustors utilize controlled mechanical linkages, springs, or electric actuators to precisely control fluid volumes, eliminating manual measurement errors while the integrated design keeps the overall system complexity manageable by using straightforward mechanical principles rather than complex electronic control systems.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device simplifies IV infusion preparation, reduces waste, minimizes contamination risks, and enhances efficiency by automating drug compounding, ensuring consistent and accurate medication delivery.
Implementation Method 1
creating a vacuum within the reconstitution apparatus to draw a liquid disposed in the first vial into the reconstitution apparatus
Implementation Method 2
compressing the reconstitution apparatus to transfer the liquid into the second vial
Implementation Method 3
creating a vacuum within the reconstitution apparatus to draw a desired volume of reconstituted drug from the second vial into the reconstitution apparatus
Implementation Method 4
compressing the reconstitution apparatus to transfer the reconstituted drug into the infusion apparatus
Implementation Method 5
creating a vacuum within the infusion apparatus to draw a base fluid into the infusion apparatus
Data Source
AI summary
A device for preparing an intravenous (IV) infusion includes: a housing; a compounding assembly disposed within the housing, the compounding assembly includes a reconstitution apparatus configured to mix a diluent with a drug to create a reconstituted drug solution and an infusion apparatus that transfers the reconstituted drug solution to an infusion bag; a reconstitution volume adjustor engages the reconstitution apparatus to control an internal volume of the reconstitution apparatus; and an infusion volume adjustor engages the infusion apparatus to control an internal volume of the infusion apparatus.


