Ixeris Chinensis Extract Preparation for UV Photoaging Delay

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Solution Overview

Problem

Current methods for obtaining Ixeris chinensis extract, such as boiling water extraction and organic solvent extraction, lead to the destruction of active ingredients and pose safety and environmental concerns, while there is a lack of research on its effectiveness in delaying ultraviolet-induced skin photoaging.

Innovation Solution

A method involving emulsification microwave extraction followed by centrifugation and vacuum concentration to produce an Ixeris chinensis extract with a total flavonoid content of 30000 ppm to 37000 ppm, which includes coarsely grinding the plant material, mixing with a first solution, microwave extraction, centrifugation, ion equilibration, and vacuum concentration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If boiling water extraction or organic solvent extraction is used to obtain Ixeris chinensis extract, then the extraction process is simple and fast, but the active ingredients are destroyed and safety and environmental concerns arise

Engineering Contradiction:

Improveextraction speedVSAvoidactive ingredient integrity

Core Design Contradiction:

ProductivityVSReliability

Solution Approach 1:

The patent changes the extraction parameters from high-temperature boiling water or organic solvents to low-temperature (4-25°C) aqueous alcohol extraction, preserving active ingredients while maintaining extraction efficiency. The temperature and solvent composition are optimized to balance extraction speed and ingredient integrity

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent uses an aqueous alcohol solution as an inert extraction medium that avoids the harmful effects of organic solvents. The alcohol-water mixture creates a safe, environmentally friendly extraction environment that prevents degradation of sensitive active ingredients while maintaining high extraction productivity

Inventive Principle:

Principle #39Inert atmosphere (Inert environment)

2Ease of manufacture

If conventional extraction methods are used, then the process is straightforward, but safety and environmental damage occur due to chemical additives and petrochemical sources

Engineering Contradiction:

Improveprocess simplicityVSAvoidskin irritation and environmental damage

Core Design Contradiction:

Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent replaces expensive and harmful organic solvents with a simple, safe aqueous alcohol solution that can be easily prepared and disposed of. The extraction medium is biodegradable and non-toxic, eliminating environmental persistence issues while maintaining manufacturing simplicity

Inventive Principle:

Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The aqueous alcohol solution acts as a safe intermediary medium between the plant material and the final product. It facilitates extraction without introducing harmful chemicals, and can be completely removed by evaporation, leaving only the pure extract without residual solvents that could cause skin irritation

Inventive Principle:

Principle #24Intermediary (Mediator)

3Quantity of substance

If existing Ixeris chinensis extracts are used, then they are available on the market, but there is no proven effectiveness in delaying ultraviolet-induced skin photoaging

Engineering Contradiction:

Improveextract availabilityVSAvoidanti-photoaging efficacy

Core Design Contradiction:

Quantity of substanceVSReliability

Solution Approach 1:

The patent performs preliminary optimization of the extraction process to maximize the concentration of anti-photoaging active ingredients. By pre-determining the optimal extraction conditions (temperature, solvent ratio, time), the resulting extract has proven efficacy for delaying UV-induced skin photoaging, addressing the reliability gap in existing products

Inventive Principle:

Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The extract effectively absorbs UV light, promotes skin fibroblast activity, protects cells from UVA-induced damage, reduces oxidative damage and DNA damage, and inhibits melanin production, thereby delaying photoaging.

Implementation Method 1

The extract effectively absorbs UV light

Methodology Applied

Scientific EffectUV light absorption: Absorption (EM radiation)

Implementation Method 2

microwave extraction

Methodology Applied

Scientific EffectMicrowave heating: Dielectric Heating

Implementation Method 3

centrifugation

Methodology Applied

Scientific EffectCentrifugal separation: Centrifugal Separation

Implementation Method 4

vacuum concentration

Methodology Applied

Scientific EffectVacuum evaporation: Vacuum Distillation

Data Source

PatentUS20260041625A1Use of ixeris chinensis extract for delaying UV-induced skin photoaging, method for preparing ixeris chinensis extract, and ixeris chinensis extract

Publication Date: 2026.02.12 KOI CORP

AI summary

Disclosed is the use of an Ixeris chinensis extract for delaying UV-induced skin photoaging, a method for preparing Ixeris chinensis extract, and an Ixeris chinensis extract. The preparation method involves preparing Ixeris chinensis coarse material and performing emulsification microwave extraction. The resulting Ixeris chinensis extract has a total flavonoid content of 30000-37000 ppm as measured by an aluminum chloride flavonoid method. This extract can absorb UV light, promote skin fibroblast activity, protect cells from UVA-induced oxidative and DNA damage, and reduce melanin production in cells, thereby preventing or delaying the UV-induced photoaging.