Jet-Printed Porous Pharmaceutical Forms for Individual Dosing
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Solution Overview
Problem
Existing pharmaceutical forms lack the capability for fast delivery of individual medicine dosages without additional dosing devices and do not support simple production methods, limiting their application range and dosage control.
Innovation Solution
A finished pharmaceutical form utilizing water-insoluble porous media, such as filtering paper or unwoven cloth, is developed, allowing for individual medicine dosing through jet printing, with the medicine applied homogeneously and marked for fragmentation, and capable of desorbing into a solution upon submersion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If conventional pharmaceutical forms are used, then production is simple, but individual medicine dosing capability is lost
Solution Approach 1:
The pharmaceutical form is divided into multiple separate dosing units (e.g., 50 tablets in one container, 100 in another) that can be individually selected and dosed. Each container holds a specific quantity of tablets corresponding to a predetermined dosage, allowing flexible individual dosing while maintaining simple production processes.
Solution Approach 2:
The desired medicine dosage is pre-calculated and pre-packaged in containers with specific quantities of tablets. The dosing information and container selection are prepared in advance, eliminating the need for complex dosing devices or calculations during administration while enabling precise individual dosing.
2Measurement precision
If additional dosing devices are used, then individual medicine dosing precision is improved, but device complexity increases
Solution Approach 1:
The dosing function is extracted from complex mechanical or electronic devices and embedded directly into the pharmaceutical form itself through predetermined packaging quantities. The container design and labeling provide the dosing information, eliminating the need for separate dosing devices while maintaining precision.
Solution Approach 2:
The pharmaceutical form itself provides the dosing capability through its design - each container is pre-filled with a specific number of tablets corresponding to the required dosage. The user simply selects the appropriate container based on the prescribed dose, making the system self-sufficient without requiring external dosing equipment.
3Ease of manufacture
If conventional pharmaceutical forms are used, then production process is simple, but dosage control flexibility is limited
Solution Approach 1:
The system provides dynamic dosage adjustment capability by offering multiple container sizes with different tablet quantities (e.g., 50, 100, 150 tablets) that can be selected based on the specific patient requirements. This flexible dosing approach is achieved through simple packaging variations rather than complex production processes.
Solution Approach 2:
The dosage flexibility is achieved by varying the quantity parameter of tablets per container while maintaining the same basic pharmaceutical form and production process. Different container sizes with specific tablet counts allow adaptation to different dosing requirements without changing the fundamental manufacturing methodology.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution simplifies pharmaceutical production, broadens the range of applicable medicines, and enables precise individual dosing without additional equipment, enhancing consumer convenience and flexibility.
Implementation Method 1
water-insoluble porous media wherein said porous media is selected such as to provide for the quantity desorption capability of the medicine applied onto said media
Implementation Method 2
capable of quantitative desorption to solution after porous media submersion into water
Data Source
AI summary
According to some embodiments, a method and system are provided comprising receiving a first quantity of at least one medicine in at least one cartridge of a plurality of cartridges of a printing device; receiving a porous media in the printing device; dispensing a first drop of the at least one medicine onto the porous media; and drying the dispensed drop on the porous media. Numerous other aspects are provided.