Joint Estimation Attenuation Correction for Respiratory Motion Artifacts

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Solution Overview

Problem

Multi-modality imaging systems face challenges in image quality due to patient motion, particularly respiratory motion, which causes inaccuracies in attenuation correction between CT and PET/SPECT images, leading to mismatches in attenuation correction factors.

Innovation Solution

The method involves acquiring a CT dataset to determine lung border information, generating a border mask, and applying joint attenuation-activity estimation techniques to reconstruct emission tomography datasets, combining them into a reconstructed image, while using activity estimation for voxels outside the border mask and joint estimation for those inside, to improve accuracy and reduce mismatches.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If standard attenuation correction using CT data is applied to PET emission data, then the reconstruction process is simple and fast, but image accuracy deteriorates due to respiratory motion causing mismatch between CT attenuation factors and PET emission information

Engineering Contradiction:
Improveattenuation correction accuracyVSAvoidreconstruction complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the image space into three distinct regions based on lung border information: lung region, border region, and non-lung region. Different reconstruction techniques are applied to each segment - standard attenuation correction for non-lung regions, joint estimation for border regions, and activity estimation for lung regions. This segmentation allows the system to improve accuracy in motion-affected areas without applying complex algorithms uniformly across the entire image, thus balancing accuracy improvement with computational complexity management.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies different reconstruction qualities to different spatial locations based on their susceptibility to respiratory motion. Border regions surrounding the lungs, which are most affected by motion, receive the most sophisticated joint attenuation-activity estimation treatment. Lung regions receive activity estimation, while stable non-lung regions receive standard attenuation correction. This local quality approach ensures computational resources are concentrated where they provide the most benefit, improving overall accuracy without uniformly increasing complexity.

Inventive Principle:
Principle #3Local quality

2Measurement precision

If joint attenuation-activity estimation is applied to all voxels, then measurement precision improves, but processing time and computational resources increase significantly

Engineering Contradiction:
Improvequantitation accuracyVSAvoidreconstruction time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent divides the emission data into three segments based on spatial location relative to lung borders: lung voxels, border voxels, and non-lung voxels. Only border voxels undergo the computationally intensive joint attenuation-activity estimation process, while lung and non-lung voxels use faster estimation methods. This segmentation strategy concentrates computational effort on the most critical motion-affected regions, achieving improved quantitation accuracy where needed while maintaining fast processing for the majority of the image volume.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies the sophisticated joint estimation technique partially - only to border regions where it provides the most value - rather than excessively applying it to the entire image. This partial action approach achieves the necessary improvement in measurement precision for motion-affected areas without the prohibitive computational cost of universal application, optimizing the trade-off between accuracy and processing time.

Inventive Principle:
Principle #16Partial or excessive action

3Reliability

If attenuation correction is performed without accounting for respiratory motion, then the reconstruction process is fast and simple, but image quality deteriorates due to mismatches between CT and PET data

Engineering Contradiction:
Improveimage qualityVSAvoidprocessing complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the image based on lung border detection and applies different processing strategies to each segment. Border regions, which are most susceptible to respiratory motion artifacts, receive joint attenuation-activity estimation that accounts for motion effects. This segmentation approach improves reliability in the most problematic regions without requiring complex motion correction for the entire image, thus improving image quality with moderate increases in processing complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent enhances image quality locally in border regions by applying joint estimation techniques specifically where respiratory motion causes mismatches between CT and PET data. Non-lung regions maintain standard attenuation correction since they are less affected by motion. This local quality improvement strategy increases reliability where it matters most while keeping overall processing complexity manageable.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS9336614B1Methods and systems for performing joint estimation techniques in image reconstruction
Publication Date: 2016.05.10 GE PRECISION HEALTHCARE LLC
  • US9336614B1 patent drawing
  • US9336614B1 patent drawing
  • US9336614B1 patent drawing

AI summary

A method for correcting an emission tomography image includes obtaining a first modality image dataset, identifying areas in the first modality dataset that may be impacted by respiratory motion, and applying joint estimation attenuation correction techniques to improve emission image data. A medical imaging system is also described herein. Emission tomography may include positron emission tomography (PET) and single photon emission computed tomography (SPECT).