Joint Injection Positioning Device for Safe Periarticular Delivery
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current methods for administering active substances to treat rheumatic diseases, such as rheumatoid arthritis and psoriatic arthritis, face challenges in achieving high local concentrations near the joint while minimizing systemic side effects and avoiding injury to the joint capsule.
Innovation Solution
A device comprising two clamping jaws to hold a skin fold near a joint, allowing for a reproducible and safe injection of substances without directly penetrating the joint capsule, thereby ensuring high local concentrations of active substances.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a simple periarticular injection with a syringe or injector pen is used, then the injection can be performed, but it is very difficult to perforate only the tissue lying on the joint capsule and inject a small amount of active substance there without touching or injuring the joint capsule
Solution Approach 1:
The patent introduces a positioning device as an intermediary tool between the injector and the joint capsule. This device includes a positioning element that can be positioned on the skin surface and a guide element that guides the injector to the correct insertion depth and angle, thereby preventing direct contact with the joint capsule while enabling precise tissue penetration for injection.
Solution Approach 2:
The positioning device is applied to the skin surface before injection to establish the correct positioning and depth. The guide element is pre-positioned to indicate the optimal insertion path, allowing the injector to follow a predetermined safe trajectory that avoids the joint capsule from the outset.
2Object-affected harmful factors
If an insertion with a basically very shallow depth is used to ensure a safe distance between the cannula and the joint capsule, then joint capsule injury is avoided, but the tissue covering joint capsules varies greatly in terms of its thickness from joint to joint and from patient to patient
Solution Approach 1:
The positioning device incorporates adjustable components that can adapt to varying tissue thicknesses. The guide element can be positioned at different depths, and the positioning element can be adjusted to accommodate different anatomical variations, allowing the device to maintain safe distance from the joint capsule while adapting to individual patient anatomy.
Solution Approach 2:
The device allows for parameter adjustments in terms of insertion depth and positioning angle based on the specific joint and patient anatomy. The guide element can be positioned at varying depths to accommodate different tissue thicknesses, ensuring both safety and adaptability across different patients and joints.
3Quantity of substance
If systemic drug therapy is used to treat rheumatic diseases, then active substances can be administered, but only relatively low serum concentrations can be achieved and higher serum concentrations would cause undesirable side effects such as damage to the kidneys and liver
Solution Approach 1:
The patent enables local injection of active substances directly into the tissue near the joint capsule, creating a localized high concentration at the target site while avoiding systemic circulation. This local quality approach delivers the full therapeutic dose to the affected area without subjecting the entire body to high concentrations, thereby preventing kidney and liver damage.
Solution Approach 2:
The positioning device acts as an intermediary that enables precise local delivery of the active substance. By guiding the injector to the exact location near the joint capsule and controlling the injection depth, the device ensures that the active substance is deposited locally rather than systemically, achieving high local concentration without systemic side effects.
4Reliability
If the concentrations of active substances are increased at the destination to achieve better immunomodulatory effect, then treatment efficacy is improved, but higher serum concentrations cause undesirable side effects
Solution Approach 1:
The device enables concentration of the active substance locally at the joint capsule tissue through controlled injection, achieving high local concentration for improved immunomodulatory effect while avoiding systemic circulation. This local quality delivery ensures that the therapeutic effect is concentrated where needed without causing systemic side effects.
Solution Approach 2:
The positioning device serves as an intermediary that facilitates precise local delivery of active substances. By controlling the injection parameters and guiding the cannula to the correct position, the device ensures that high concentrations are achieved locally for effective treatment while preventing systemic absorption that would cause harmful side effects.
Data Source
AI summary
A device for positioning an injector near a joint and to a device for injecting a substance near a joint. A device for positioning an injector near a joint comprises two clamping jaws for holding in place a skin fold in a clamping position and an interface for mechanically connecting an injector. This makes possible a safe, reproducible and simple injection of substances in the immediate vicinity of a joint.