Keyed Cartridge Insertion Mechanism for Tolerance and Thermal Alignment

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Solution Overview

Problem

Existing fluid delivery devices face issues with cartridge insertion due to length tolerance and thermal expansion, leading to compressible gaps and misaligned needle insertion, which affect accurate medicament delivery in hydraulically driven systems.

Innovation Solution

A cartridge insertion mechanism with a keyed feature on the cartridge that mates with corresponding features in the hydraulic drive unit, ensuring proper alignment and minimizing compressible gaps, while compensating for thermal expansion effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If cartridges are manufactured with standard length tolerances, then manufacturing cost is reduced, but compressible gaps occur during insertion affecting delivery accuracy

Engineering Contradiction:
Improvecartridge length toleranceVSAvoidmedicament delivery accuracy
Core Design Contradiction:
Manufacturing precisionVSReliability

Solution Approach 1:

The seal member is designed as a compressible element (e.g., elastomeric material) that dynamically adapts to cartridges of varying lengths. The compressibility allows the seal to maintain contact and sealing function across a range of cartridge lengths, accommodating manufacturing tolerances while preventing harmful fluid communication.

Inventive Principle:
Principle #15Dynamics

2Manufacturing precision

If the device structure is made rigid to maintain alignment, then alignment precision is improved, but thermal expansion effects cause misalignment

Engineering Contradiction:
Improveneedle-to-septum alignmentVSAvoidthermal expansion effect
Core Design Contradiction:
Manufacturing precisionVSTemperature

Solution Approach 1:

The seal member's material properties (compliance, durometer) are selected to provide thermal compensation. The elastomeric material expands and contracts with temperature changes, maintaining the sealed relationship between the needle assembly and cartridge septum across varying temperatures, thereby preserving alignment precision.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If compressible gaps are minimized through tight tolerances, then delivery accuracy is improved, but device complexity increases

Engineering Contradiction:
Improvefluid delivery accuracyVSAvoidinsertion mechanism complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The compressible seal member automatically compensates for length variations and maintains sealing without requiring active control mechanisms, sensors, or complex adjustment systems. The elastic deformation of the seal itself provides the corrective action, simplifying the overall device architecture while ensuring accurate fluid delivery.

Inventive Principle:
Principle #25Self-service

4Adaptability or versatility

If the seal member is made highly compliant to accommodate length variations, then adaptability is improved, but sealing effectiveness deteriorates

Engineering Contradiction:
Improvecartridge length accommodationVSAvoidseal integrity
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The seal member exhibits different degrees of compliance in different regions or aspects: highly compliant in the axial direction to accommodate length variations, while maintaining sufficient radial stiffness and structural integrity to ensure effective sealing. This localized differentiation of mechanical properties resolves the contradiction between adaptability and sealing effectiveness.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS12465681B2Cartridge insertion mechanism for a fluid delivery device
Publication Date: 2025.11.11 MANNKIND CORP
  • US12465681B2 patent drawing
  • US12465681B2 patent drawing
  • US12465681B2 patent drawing

AI summary

A fluid delivery device comprises a drive unit including an actuator and one or more first features and a cartridge filled with a fluid prior to being inserted into the housing. The cartridge having a fluid reservoir sealed at one end by a movable piston and sealed at another end by a pierceable septum. The cartridge includes one or more second features that are configured to align and mate with the one or more first features allowing the cartridge to be inserted into the drive unit. The piston is moveabe by the actuator once the cartridge is inserted into the drive unit.