Keyed Fluid Storage for Clinical Analyzer Reagent Supply

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Solution Overview

Problem

Clinical analyzers face challenges in accurately and efficiently supplying various reagents to multiple detection units, which affects the throughput and cost-effectiveness of analytical tests, particularly in systems using luminescent and ion-selective measurements.

Innovation Solution

A fluid storage system with physically keyed compartments and barcoding ensures correct installation of consumables, combined with a manifold for gravity-fed delivery and fluid counters to manage reagent levels, preventing leakage and alerting operators when supplies are low.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple detection units with different analytical detectors are used to perform various tests, then the analytical options and test versatility are increased, but the complexity of accurately supplying various reagents to each detection unit increases

Engineering Contradiction:
Improveanalytical optionsVSAvoidreagent supply complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The fluid storage system is divided into multiple separately keyed compartments, each dedicated to storing a specific reagent or fluid type. This segmentation allows each compartment to be independently managed and supplied to specific detection units, reducing the complexity of managing a single complex supply system for multiple detectors.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Each compartment is equipped with a unique physical key pattern that is asymmetric and specific to that compartment. This asymmetric keying system ensures that only the correct compartment can be installed in its designated location, preventing incorrect reagent installation and simplifying the operator's task of ensuring proper reagent placement in a multi-detection unit system.

Inventive Principle:
Principle #4Asymmetry

2Reliability

If physically keyed compartments are used to prevent incorrect fluid installation, then the reliability of reagent supply is improved, but the device complexity increases

Engineering Contradiction:
Improvereagent supply accuracyVSAvoidcompartment keying structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Each compartment features a unique asymmetric physical key pattern that must match its corresponding slot. This simple yet effective asymmetric design ensures that only the correct compartment can be physically installed in the correct location, providing high reliability with minimal structural complexity.

Inventive Principle:
Principle #4Asymmetry

Solution Approach 2:

The physical keying system provides automatic self-checking functionality. When an operator attempts to install a compartment, the key pattern automatically verifies compatibility with the slot, eliminating the need for additional verification steps or complex control systems to ensure correct reagent installation.

Inventive Principle:
Principle #25Self-service

3Productivity

If barcoding and fluid counters are implemented to track reagent levels, then the productivity and operational efficiency are improved, but the device complexity increases

Engineering Contradiction:
Improveoperational efficiencyVSAvoidtracking system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

Each compartment is pre-labeled with a barcode containing identification information before installation. This preliminary action allows the system to automatically identify and track each reagent compartment upon installation, enabling efficient inventory management and reducing operational complexity through automated data capture.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Fluid counters are implemented to continuously monitor and provide feedback on reagent levels in each compartment. This feedback mechanism allows the system to automatically track consumption, alert operators when reagents are low, and manage inventory efficiently, improving productivity through automated monitoring rather than manual checking.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Ensures accurate and uninterrupted supply of reagents to detection units, enhancing test efficiency and reducing costs by preventing incorrect fluid installation and optimizing reagent usage.

Implementation Method 1

The fluids are then gravity fed into reservoirs which are controlled by two position level sensors.

Methodology Applied
Scientific EffectGravity: Gravitation

Implementation Method 2

reservoirs which are controlled by two position level sensors

Methodology Applied
Scientific EffectLevel sensing:

Implementation Method 3

A filtered vent is provided to allow fluid flow

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 4

Each consumable will be bar coded prior to installation

Methodology Applied
Scientific EffectOptical scanning:

Data Source

PatentEP1960793B1Storage and supply system for clinical solutions used in an automatic analyzer
Publication Date: 2018.09.12 SIEMENS HEALTHCARE DIAGNOSTICS INC
  • EP1960793B1 patent drawingFigure 1
  • EP1960793B1 patent drawingFigure 2
  • EP1960793B1 patent drawingFigure 3

AI summary

A fluid handling system adapted to provide storage and supply of a number of liquid solutions to an automatic clinical analyzer having three different bottle-like containers, a collapsible plastic-metal-plastic pouch having a mouth-like opening, a fitment to be sealed within mouth-tike opening, a septum within the fitment, and open meal band or cap to seal the septum into the fitment.