Kidney-Shaped Balloon Dilator for Upper Esophageal Sphincter

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Solution Overview

Problem

Current esophageal dilators are cylindrical and do not accurately approximate the biomechanical dimensions of the upper esophageal sphincter, which is kidney bean shaped, leading to ineffective dilation and potential scarring from radiation-induced fibrosis.

Innovation Solution

A balloon dilator designed to resemble a kidney shape or two cylindrical dilators in apposition, made from non-compliant or semi-compliant materials, which can be differentially inflated and may include a drug delivery system, to anatomically complement the upper esophageal sphincter, potentially using a single or dual catheter system for inflation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Shape

If cylindrical dilators with round circumference are used, then the device structure is simple and easy to manufacture, but the dilator does not accurately approximate the kidney bean shape of the upper esophageal sphincter, leading to ineffective dilation

Engineering Contradiction:
Improveshape approximation of UESVSAvoiddevice fabrication complexity
Core Design Contradiction:
ShapeVSEase of manufacture

Solution Approach 1:

The dilator is divided into multiple segments or lobes that can be independently shaped to match the kidney bean geometry of the UES. This segmentation allows the dilator to conform to the complex anatomical shape while maintaining manufacturing feasibility through modular construction techniques.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The dilator design transitions from a symmetric cylindrical shape to an asymmetric kidney bean shape that accurately reflects the anatomical geometry of the upper esophageal sphincter. This asymmetric design enables better approximation of the target tissue shape, improving dilation effectiveness.

Inventive Principle:
Principle #4Asymmetry

2Stability of the object's composition

If non-compliant or semi-compliant materials are used for the balloon dilator, then the dilator maintains its shaped configuration for effective UES approximation, but the device requires more complex inflation control mechanisms

Engineering Contradiction:
Improveballoon shape stabilityVSAvoidinflation control system
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The balloon dilator incorporates dynamic inflation control that allows transition between different inflation states. The system can be inflated to different pressures and volumes depending on the specific anatomical requirements, providing adaptability while maintaining shape stability through controlled material properties.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The dilator utilizes changes in inflation parameters (pressure, volume, rate) to achieve the desired shape approximation and dilation effect. By carefully controlling these parameters, the system maintains shape stability while avoiding the need for overly complex mechanical control mechanisms.

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If a single catheter system is used to deliver the balloon dilator, then the device delivery is simpler, but the ability to differentially inflate different portions of the dilator is limited

Engineering Contradiction:
Improvecatheter system structureVSAvoiddifferential inflation capability
Core Design Contradiction:
Device complexityVSAdaptability or versatility

Solution Approach 1:

The catheter system employs a nested structure where multiple inflation lumens are contained within a single outer catheter sheath. This nesting arrangement allows for differential inflation of different balloon segments through a unified delivery system, maintaining simplicity while enabling versatile inflation patterns.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The single catheter system is designed with multiple functions integrated into one structure, including separate inflation lumens for differential balloon inflation, drug delivery capabilities, and positioning control. This multi-functionality achieves adaptability without requiring multiple separate catheters.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The balloon dilator effectively expands the upper esophageal sphincter, reducing scarring and allowing for therapeutic substance delivery, thereby improving tissue remodeling and treatment outcomes.

Implementation Method 1

The balloons are configured to be differentially inflated

Methodology Applied
Scientific EffectMechanical expansion: Pressure Increase

Implementation Method 2

made from non-compliant or semi-compliant materials

Methodology Applied
Scientific EffectMaterial compliance: Elasticity

Data Source

PatentEP2846869B1Upper esophageal sphincter dilator
Publication Date: 2024.09.25 RGT UNIV OF CALIFORNIA
  • EP2846869B1 patent drawingFigure 1A
  • EP2846869B1 patent drawingFigure 1B
  • EP2846869B1 patent drawingFigure 1C

AI summary

An apparatus for dilating an upper esophageal sphincter. The apparatus includes an elongated expandable member having a cross-section shaped to support a natural shape of an upper esophageal sphincter. A catheter extends from the elongated inflatable member.