Kinematic Substrate Holder for Deformation-Free Imaging

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Solution Overview

Problem

Existing systems face challenges in consistently and predictably securing substrates of varying sizes and shapes for imaging, as they may deform or impart moments on the substrate, leading to inconsistent image quality due to substrate inconsistencies or deformities.

Innovation Solution

A system comprising a holder and gripper with kinematic mounts, including securing blocks and a secure bar, that accommodate different substrate sizes and shapes by providing multiple points of contact and adjustable components, ensuring secure and repeatable positioning without deforming the substrate.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If traditional substrate securing methods are used, then substrates can be held in place for imaging, but the substrates may deform or be subjected to moments, leading to inconsistent positioning and image quality

Engineering Contradiction:

Improvesubstrate positioning consistencyVSAvoidsubstrate deformation

Core Design Contradiction:

Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The substrate securing mechanism is divided into multiple independent kinematic mounting points (at least three non-collinear points) that independently contact the substrate. Each mounting point provides localized support without imposing forces that would deform the substrate, allowing the substrate to be secured while maintaining its natural state and consistent positioning.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

Kinematic mounting elements act as intermediaries between the substrate and the imaging system. These elements provide contact points that support the substrate without creating harmful moments or deformation forces, enabling secure positioning while protecting substrate integrity.

Inventive Principle:

Principle #24Intermediary (Mediator)

2Adaptability or versatility

If a fixed securing mechanism is used, then the substrate can be held firmly, but it cannot accommodate substrates of varying sizes and shapes

Engineering Contradiction:

Improvesubstrate size and shape accommodationVSAvoidsecuring consistency

Core Design Contradiction:

Adaptability or versatilityVSReliability

Solution Approach 1:

The kinematic mounting system is designed with universal adaptability to accommodate substrates of varying sizes, shapes, and configurations. The system uses multiple adjustable mounting points that can be positioned to suit different substrate geometries while maintaining consistent securing reliability through the kinematic principle of defined contact points.

Inventive Principle:

Principle #6Universality (Multi-functionality)

Solution Approach 2:

The securing mechanism incorporates dynamic adjustability where mounting points can be repositioned or adjusted to accommodate different substrate configurations. This dynamic capability allows the same mechanism to reliably secure various substrate types without deformation by adapting the contact point locations.

Inventive Principle:

Principle #15Dynamics

3Productivity

If manual substrate loading is used, then flexibility in handling is maintained, but time consumption and human error increase

Engineering Contradiction:

Improveloading speedVSAvoidpositioning accuracy

Core Design Contradiction:

ProductivityVSReliability

Solution Approach 1:

The kinematic mounting system is designed to automatically secure substrates through self-aligning contact points. The substrate itself guides the positioning process by engaging with the defined kinematic mounting points, eliminating the need for manual alignment while ensuring consistent and accurate positioning every time.

Inventive Principle:

Principle #25Self-service

Solution Approach 2:

The system replaces manual mechanical manipulation with an automated kinematic mounting mechanism. Instead of relying on human operators to position substrates manually, the automated system uses predefined kinematic contact points to securely and accurately position substrates consistently, improving both speed and reliability.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively secures substrates across various sizes and shapes, maintaining a consistent surface and preventing deformation, thereby ensuring reliable and repeatable imaging and processing by minimizing friction and abrasion through the use of materials like tungsten carbide and spring-loaded mechanisms.

Implementation Method 1

spring-loaded mechanisms

Methodology Applied

Scientific EffectElasticity: Elasticity

Data Source

PatentUS10802260B2Automated substrate loading

Publication Date: 2020.10.13 RARECYTE INC

AI summary

This disclosure is directed to system for transferring a substrate, such as a microscope slide, and holding the substrate within at least one device. The system includes a holder for holding the substrate and a gripper for transferring the substrate, such as between a cassette or stack and the holder. A method is also discussed herein.