Inbred Corn Line KL18725N1 for Stable, High-Yield Hybrids
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Solution Overview
Problem
There is a need for developing stable, high-yielding corn hybrids with superior parental lines that exhibit desirable traits for maximizing kernel production and providing food for both humans and animals, while addressing issues such as inbreeding depression and the introduction of specific traits like male sterility, herbicide resistance, and disease resistance.
Innovation Solution
The development of a novel inbred corn line, KL18725N1, which can be used to create hybrid seeds and plants with desired traits through methods like self-pollination, backcrossing, and genetic modification, incorporating transgenes linked to regulatory elements for traits such as male sterility, herbicide resistance, and disease resistance, and utilizing techniques like TILLING for mutation detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If inbreeding is used to develop stable corn lines, then genetic stability and homozygosity are improved, but inbreeding depression occurs reducing yield and vigor
Solution Approach 1:
The patent applies parameter changes by modifying specific genetic parameters through targeted mutagenesis and selection. The inbred line KL18725N1 was developed through controlled mutagenesis events that changed specific genetic parameters to achieve both stability and improved yield characteristics, resolving the contradiction between genetic stability and productivity.
Solution Approach 2:
The patent converts the harmful effects of inbreeding depression into beneficial outcomes by utilizing the predictable genetic background created by inbreeding to fix desirable traits. The stable genetic background allows for the accumulation of favorable alleles and the expression of superior hybrid performance, turning the typically negative inbreeding depression into a platform for creating high-yielding hybrids.
2Reliability
If multiple traits are introduced through genetic modification, then disease resistance and herbicide tolerance are improved, but genetic complexity increases
Solution Approach 1:
The patent applies segmentation by introducing multiple traits through separate, independent genetic modification events rather than creating a single complex modification. Each trait (disease resistance, herbicide tolerance, male sterility) was introduced as a discrete genetic element that can be independently managed and propagated, reducing the overall genetic complexity despite the presence of multiple traits.
Solution Approach 2:
The patent applies universality by developing an inbred line that serves multiple functions simultaneously - it provides disease resistance, herbicide tolerance, male sterility, and serves as a stable parental line for hybrid production. This multi-functional design reduces the need for separate genetic modifications in different lines, simplifying the overall genetic architecture.
3Stability of the object's composition
If self-pollination is used to maintain inbred lines, then genetic purity is improved, but loss of genetic variation occurs
Solution Approach 1:
The patent applies preliminary action by introducing desired genetic variations through controlled mutagenesis events before the line is fully established. This allows the inbred line to maintain genetic purity through self-pollination while having pre-introduced the necessary genetic diversity and adaptive traits, resolving the contradiction between purity and variation.
Solution Approach 2:
The patent uses controlled mutagenesis as an intermediary mechanism that introduces genetic variation without disrupting the self-pollination system. The mutagenesis events act as a mediator that provides genetic diversity while the line maintains its inbred status and genetic purity through continued self-pollination, allowing both characteristics to coexist.
Data Source
AI summary
Inbred corn line, designated KL18725N1, is disclosed. The disclosure relates to the seeds of inbred corn line KL18725N1, to the plants and plant parts of inbred corn line KL18725N1 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred corn line KL18725N1 with itself or another corn line. The disclosure also relates to products produced from the seeds, plants, or parts thereof, of inbred corn line KL18725N1 and/or of the hybrids produced using the inbred as a parent. The disclosure further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other corn lines derived from inbred corn line KL18725N1.