Knowledge Distillation for Low-Noise Medical Image Enhancement

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Solution Overview

Problem

Current medical imaging techniques suffer from low signal to noise (SNR) and contrast to noise (CNR) ratios, leading to image artifacts that degrade image quality and hinder accurate diagnosis and treatment, particularly in real-time surgical environments.

Innovation Solution

A knowledge distillation based training method using a cGAN machine learning model to generate a reduced noise dataset, which is then used to train a UNET model for efficient and accurate image enhancement, reducing noise levels and improving SNR and CNR.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If current medical imaging techniques are used, then image scanning and generation capabilities can be improved, but signal to noise ratio and contrast to noise ratio remain low resulting in image artifacts

Engineering Contradiction:
Improveimage qualityVSAvoidnoise and artifacts
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an intermediary processing step between image acquisition and final output. A trained machine learning model acts as a mediator that receives low-quality images with noise and artifacts, processes them through learned transformations, and outputs enhanced images with improved SNR and CNR. This intermediary model bridges the gap between current imaging capabilities and desired image quality.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent transforms the image data by changing key parameters such as signal-to-noise ratio and contrast-to-noise ratio through machine learning-based processing. The model learns optimal parameter transformations during training on paired datasets, enabling it to adjust noise levels, contrast enhancement, and overall image quality metrics without requiring changes to the physical imaging equipment.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If image scanning time is reduced for real-time surgical environments, then productivity is improved, but image quality and noise reduction capability deteriorate

Engineering Contradiction:
Improvescan timeVSAvoidimage quality
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent performs preliminary action by pre-training machine learning models on extensive datasets of paired low-quality and high-quality images before deployment. This offline training phase allows the model to learn complex noise patterns and enhancement strategies in advance, so that during real-time surgical procedures, the model can rapidly process images without requiring lengthy processing times or sacrificing quality.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent creates a virtual copy of the ideal high-quality imaging process through the trained machine learning model. Instead of physically acquiring images at higher quality settings (which would increase scan time), the model generates a computational copy of what a high-quality image would look like, based on the rapidly acquired low-quality input. This copying approach maintains productivity while achieving enhanced image quality.

Inventive Principle:
Principle #26Copying

3Measurement precision

If complex image processing is applied to reduce noise, then image quality is improved, but computational burden and processing time increase

Engineering Contradiction:
Improvenoise reductionVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs the computationally intensive work of learning optimal noise reduction strategies during an offline training phase. The machine learning model is trained on large datasets using complex algorithms and significant computational resources beforehand. Once trained, the model contains compressed knowledge that can be rapidly applied during real-time processing, transferring the computational burden from the deployment phase to the training phase.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces traditional mechanical or algorithmic image processing methods with a data-driven machine learning approach. Instead of applying fixed mathematical filters or iterative optimization algorithms during processing, the system uses a pre-trained neural network that has learned effective processing patterns from data. This substitution enables faster processing while maintaining or improving noise reduction performance.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentEP4625346A1Knowledge distillation based machine learning models for medical image enhancement
Publication Date: 2025.10.01 PERIMETER MEDICAL IMAGING AI INC
  • EP4625346A1 patent drawingFigure 1
  • EP4625346A1 patent drawingFigure 2
  • EP4625346A1 patent drawingFigure 3A

AI summary

At least a method for training a target machine learning model for enhancing a digital image processing is provided. The method comprises receiving a first data set including a first plurality of digital images, training a first machine learning model using the first data set and a second data set including a second plurality of digital images, generating, by the first machine learning model that is trained, a target data set including a third plurality of digital images, the third plurality of digital images having noise represented by respective noise values that are lower than the noise represented by the respective noise values of the first plurality of digital images, and training the target machine learning model using the target data set and the first data set including the first plurality of digital images for enhancing at least one characteristic of a new digital image.