Synergistic L-glufosinate Herbicide Combinations for Resistant Amaranthus Control

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Solution Overview

Problem

Current herbicides are insufficient for controlling resistant and persistent Amaranthus genus weeds, such as Amaranthus hybridus and Amaranthus viridis, and often result in additive or antagonistic effects, leading to phytotoxicity in crops.

Innovation Solution

A synergistic herbicidal combination comprising L-glufosinate, its salts, esters, or combinations thereof, and at least one additional herbicide selected from protoporphyrinogen oxidase inhibitor herbicides, auxin mimics herbicides, and acetolactate synthase inhibitor herbicides, applied to control Amaranthus genus weeds.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If single herbicides or conventional herbicidal combinations are used to control Amaranthus genus weeds, then the herbicides can be applied to target weeds, but they fail to effectively control resistant and persistent Amaranthus weeds

Engineering Contradiction:
Improveweed control effectivenessVSAvoidherbicide resistance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines L-glufosinate with at least one additional herbicide from specific chemical classes (protoporphyrinogen oxidase inhibitors, acetyl CoA carboxylase inhibitors, auxin mimics, acetolactate synthase inhibitors, or hydroxyphenyl pyruvate dioxygenase inhibitors) that have different modes of action. This merging of herbicides with different biochemical pathways overcomes resistance mechanisms that have developed against individual herbicides, achieving effective control of resistant Amaranthus weeds while managing resistance development.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite herbicidal formulation comprising L-glufosinate and at least one additional herbicide from specified chemical classes. This composite approach integrates multiple active ingredients with complementary modes of action, where L-glufosinate inhibits glutamine synthetase and the partner herbicides target different biochemical pathways, resulting in synergistic or additive effects that overcome resistance and provide reliable weed control.

Inventive Principle:
Principle #40Composite materials

2Reliability

If herbicidal combinations are used to control resistant weeds, then weed control effectiveness improves, but phytotoxicity to crops increases

Engineering Contradiction:
Improveweed control effectivenessVSAvoidphytotoxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes the concentration parameters of L-glufosinate and the additional herbicide within specific ranges to achieve effective weed control while minimizing crop phytotoxicity. By carefully controlling the dosage and ratio of each active ingredient, the formulation maintains synergistic effectiveness against resistant Amaranthus weeds while reducing harmful effects on non-target crops through precise parameter optimization.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If higher doses of herbicides are used to control persistent Amaranthus weeds, then weed control effectiveness improves, but the risk of herbicide resistance development increases

Engineering Contradiction:
Improveweed control effectivenessVSAvoidherbicide resistance risk
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines L-glufosinate with at least one additional herbicide from specific chemical classes that have different modes of action. This merging approach allows for effective control at optimized doses while reducing resistance risk because the weeds must simultaneously develop resistance to multiple different biochemical pathways, which is statistically much less likely than developing resistance to a single herbicide.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS20250160332A1Herbicidal combinations and a method for controlling undesired vegetation
Publication Date: 2025.05.22 UPL MAURITIUS LTD
  • US20250160332A1 patent drawing

AI summary

The present disclosure relates to a method for controlling unwanted vegetation/weeds. More particularly, the present disclosure relates to a method for controlling Amaranthus genus weeds with synergistic herbicidal combinations comprising L-glufosinate, salts, esters, or combinations thereof and at least one additional herbicide.