Lactobacillus plantarum L-137 Composition for Fatigue and Sleep Disorders

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing treatments do not effectively address fatigue, sleep disorders, and menopausal symptoms, particularly those caused by psychological or physical stress, with Lactobacillus plantarum L-137 not previously recognized for these benefits.

Innovation Solution

A composition comprising Lactobacillus plantarum L-137 or its processed products is developed to treat, prevent, or improve fatigue, sleep disorders, and menopausal symptoms, including specific conditions such as vasomotor disorders and eye strain, through oral or injectable administration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional treatments are used for fatigue, sleep disorders, and menopausal symptoms, then existing treatments are applied, but they do not effectively address these symptoms particularly those caused by psychological or physical stress

Engineering Contradiction:
Improveeffectiveness of treatmentVSAvoidability to address stress-related symptoms
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent changes the biological parameter by introducing a specific probiotic strain (Lactobacillus plantarum L-137) that produces unique metabolites capable of addressing multiple symptom types including stress-related fatigue and sleep disorders, thereby improving treatment effectiveness across diverse conditions

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The composition is designed to treat multiple conditions simultaneously including fatigue, sleep disorders, eye strain, and menopausal symptoms through a single probiotic-based formulation, enhancing adaptability to address various stress-related symptoms with one versatile treatment

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If Lactobacillus plantarum L-137 is used to treat multiple symptoms, then comprehensive symptom relief is achieved, but the strain was not previously recognized for these benefits requiring extensive investigation

Engineering Contradiction:
Improverange of treatable symptomsVSAvoidtime for material investigation
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent performs preliminary screening and characterization of the L-137 strain's metabolites in advance, identifying their unique biochemical properties and therapeutic potentials before clinical application, thereby reducing the time required for subsequent investigation and development

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP4628089A1Composition for improving fatigue, sleeping disorders or eye strain and menopausal symptoms
Publication Date: 2025.10.08 HOUSE WELLNESS FOODS
  • EP4628089A1 patent drawing
  • EP4628089A1 patent drawing
  • EP4628089A1 patent drawing

AI summary

A problem to be solved by the present invention is to provide a composition for improving fatigue, sleep disorders or eye strain, and menopausal symptoms. The problem is solved by a composition comprising Lactobacillus plantarum L-137.