Lactide Stereocomplex Polymer Melt Processing

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Solution Overview

Problem

There is a need for an environmentally friendly and sustainable method to prepare a highly-elastic, lactide-based polymer system that can be processed efficiently without requiring solvent-based methods or thermal post-treatment.

Innovation Solution

A method involving the preparation of a melt of a copolymer based on L-lactide and D-lactide with a lactide-containing stereocomplex forming agent, where the stereocomplexes are formed spontaneously during thermoplastic processing, eliminating the need for thermal post-treatment and allowing for solvent-free processing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If solvent-based processes are used to prepare PLLA/PDLA blends, then the stereocomplex formation is facilitated, but the environmental friendliness and sustainability are reduced

Engineering Contradiction:
Improvestereocomplex formationVSAvoidenvironmental friendliness
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent changes the fundamental parameter of the processing medium from solvent-based to solvent-free melt processing. This parameter change enables stereocomplex formation without using harmful solvents, thus resolving the contradiction between ease of manufacture and environmental friendliness. The melt processing at elevated temperatures allows direct contact and interaction between PLLA and PDLA chains, facilitating stereocomplex formation in an environmentally benign manner.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the chemical mechanism of solvent-mediated mixing with a physical/thermal mechanism of melt processing. By heating the polymer blend to temperatures above the glass transition temperature, the polymers become mobile and can form stereocomplexes through thermal energy-driven chain mobility, eliminating the need for solvent-based chemical processing and thereby improving environmental sustainability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Stability of the object's composition

If thermal post-treatment (tempering) is applied to obtain sufficient crystallites, then the shape stability is improved, but the energy consumption and processing time increase

Engineering Contradiction:
Improveshape stabilityVSAvoidenergy consumption
Core Design Contradiction:
Stability of the object's compositionVSUse of energy by moving object

Solution Approach 1:

The patent performs preliminary action by forming stereocomplexes during the main processing step itself rather than requiring a separate subsequent tempering step. The stereocomplex formation occurs in-situ during melt processing, which preliminarily establishes the crystalline structure needed for shape stability, thereby eliminating or reducing the need for additional thermal post-treatment and associated energy consumption.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent merges the stereocomplex formation step with the main processing step into a single integrated operation. Instead of separating crystallization from processing, the method combines them so that stereocomplexes form during the extrusion or molding process itself, reducing the number of discrete steps and eliminating the need for separate thermal post-treatment, thus lowering energy consumption and processing time.

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If multiple separate steps (blend preparation, extrusion, drying, tempering) are used, then the processing completeness is ensured, but the productivity and simplicity are reduced

Engineering Contradiction:
Improveprocessing completenessVSAvoidproduction efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent merges multiple separate processing steps into a single integrated extrusion or molding operation. The blend preparation, extrusion, and stereocomplex formation are combined into one continuous process step, eliminating intermediate drying and tempering operations. This merging maintains processing completeness while significantly improving productivity by reducing the number of steps and associated handling time.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent makes the main processing step multi-functional by having it simultaneously perform blend mixing, extrusion, and stereocomplex formation. The extrusion process serves multiple purposes: it mixes the polymers, forms the desired product shape, and induces stereocomplex formation through controlled cooling, thereby eliminating the need for separate dedicated steps for each function and improving overall production efficiency.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method results in a biodegradable and biocompatible polymer system with high shape stability and elasticity, enabling cost-effective and energy-efficient production of lactide-based polymers suitable for various thermoplastic processes.

Implementation Method 1

adding a lactide-containing stereocomplex forming agent to the melt, wherein the stereocomplex forming agent is selected such that the resulting polymer system comprises a combination of constitution units derived from L-lactide and constitution units derived from D-lactide forming stereocomplexes

Methodology Applied
Scientific EffectStereocomplex formation:

Implementation Method 2

preparing a melt of a copolymer based on a first comonomer and at least one second comonomer

Methodology Applied
Scientific EffectMelting: Melting

Data Source

PatentEP3625292B1Method of preparing a physically cross-linked, lactide-based polymer system, polymer system prepared by the method, and process of manufacturing an object from the polymer system
Publication Date: 2022.07.06 HELMHOLTZ ZENTRUM HEREON GMBH
  • EP3625292B1 patent drawingFigure 1a~2b
  • EP3625292B1 patent drawingFigure 3~4
  • EP3625292B1 patent drawingFigure 5~6

AI summary

The invention provides a method of preparing a lactide-based, biodegradable (biocompatible), physically cross-linked and highly elastic polymer system. The method comprises the steps of: preparing a melt of a copolymer based on a first comonomer and at least one second comonomer, the first comonomer being selected from L-lactide and D-lactide; and adding a lactide-containing stereocomplex forming agent to the melt, wherein the stereocomplex forming agent is selected such that the resulting polymer system comprises a combination of constitution units derived from L-lactide and constitution units derived from D-lactide forming stereocomplexes.