Lactobacillus Antimicrobial Agent for Broad-Spectrum Pathogen Control
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Solution Overview
Problem
Current antimicrobial agents, including alcohols and synthetic compounds, are ineffective against alcohol-resistant spore-forming bacteria and can cause side effects such as skin irritation, while lacking efficacy against various fungi and viruses.
Innovation Solution
Development of an antimicrobial and antiviral agent utilizing Lactobacillus derived from Artemisia indica var. maximowiczii, including specific species like Lactobacillus parafarraginis, parabuchneri, buchneri, harbinensis, and vini, which are fermented to produce a secretion effective against a broad spectrum of fungi, viruses, and bacteria, including spore-forming species.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If alcohols are used as antimicrobial agents, then antimicrobial effect is achieved, but alcohol-resistant spore-forming bacteria remain unaffected and skin irritation occurs
Solution Approach 1:
The patent changes the chemical composition parameters of the antimicrobial agent by using lactic acid and its derivatives instead of alcohols, thereby maintaining antimicrobial effectiveness while eliminating skin irritation and spore resistance issues
Solution Approach 2:
The patent employs naturally occurring lactic acid produced by lactic acid bacteria, which is biodegradable and environmentally friendly, replacing persistent synthetic alcohol-based compounds
2Reliability
If synthetic compounds are used as antimicrobial agents, then antimicrobial effect is achieved, but contact dermatitis and skin irritation occur
Solution Approach 1:
The patent replaces synthetic compounds with naturally occurring lactic acid produced by lactic acid bacteria, which are biodegradable and lack the harmful properties of synthetic chemicals, thereby eliminating contact dermatitis while maintaining antimicrobial activity
Solution Approach 2:
The patent converts the natural metabolic byproduct of lactic acid bacteria (lactic acid) into a beneficial antimicrobial agent, transforming a potentially irritating substance into a safe and effective treatment through controlled production and formulation
3Reliability
If conventional antimicrobial agents are used, then bacterial infection is treated, but efficacy against fungi and viruses is lacking
Solution Approach 1:
The patent develops a universal antimicrobial formulation based on lactic acid and lactic acid bacteria that effectively targets multiple types of pathogens including bacteria, fungi, and viruses, thereby achieving multi-functionality and broad-spectrum coverage
Solution Approach 2:
The patent creates a composite antimicrobial system combining lactic acid, lactic acid bacteria, and their metabolic products, which synergistically enhance efficacy against diverse pathogen types while maintaining safety and compatibility
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The antimicrobial and antiviral agent effectively reduces microbial loads by 80% or more within 24 hours, including fungi, Gram-negative and Gram-positive bacteria, and viruses, with minimal side effects, and can be used as a therapeutic agent or disinfectant, suitable for human application and environmental surfaces.
Implementation Method 1
a fermentation liquor containing Lactobacillus
Data Source
AI summary
The present invention aims to provide an antimicrobial and antiviral agent which comprises a naturally occurring component as an active ingredient and is effective against microbes including various classes of fungi and viruses. In one aspect of the present invention, provided is an antimicrobial and antiviral agent comprising Lactobacillus derived from Artemisia indica var. maximowiczii.