Lactobacillus bulgaricus B-30892 for Neurological Conditions
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Solution Overview
Problem
Current treatments for neurological conditions and diseases, such as autism, obsessive compulsive disorder, and multiple sclerosis, primarily focus on managing symptoms with drugs that interact with the serotonin system, but these do not address the root cause of autoimmune reactions and neurotoxins affecting the nervous system.
Innovation Solution
Administering an effective amount of Lactobacillus bulgaricus B-30892 or its supernatant to neutralize antigenic and toxic substances, reducing antibody production, and interfering with neurotoxins and autoimmune responses, thereby preventing or mitigating neurological conditions and diseases.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If drugs that interact with the serotonin system are used to treat neurological conditions, then symptoms can be managed, but the root cause of autoimmune reactions and neurotoxins is not addressed
Solution Approach 1:
The patent extracts and eliminates the harmful bacteria and neurotoxins from the gastrointestinal tract using probiotics and antibiotics, rather than merely managing symptoms. This removes the root cause of autoimmune reactions and neurological conditions, addressing the fundamental problem rather than just treating manifestations.
Solution Approach 2:
The patent applies preliminary action by using probiotics to restore healthy gut flora and eliminate pathogenic bacteria before neurological damage occurs or worsens. This preventive approach addresses the root cause early in the disease process, preventing the development of full-blown neurological conditions rather than treating established symptoms.
2Reliability
If probiotics are used to improve neurological behavior, then neurological symptoms can be improved, but the mechanism of action is not fully understood
Solution Approach 1:
The patent identifies the gut-brain axis as an intermediary system connecting gastrointestinal health to neurological function. Probiotics act as mediators that restore balance in the gut microbiome, which in turn influences neurological conditions through this axis. This provides a plausible mechanism for how probiotics improve neurological symptoms without requiring complete understanding of all underlying pathways.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The use of Lactobacillus bulgaricus B-30892 has shown to improve neurological symptoms by neutralizing toxins and reducing autoimmune responses, providing a potential treatment for conditions like autism, obsessive compulsive disorder, and multiple sclerosis without suppressing the immune system.
Implementation Method 1
Administering an effective amount of Lactobacillus bulgaricus B-30892 or its supernatant to neutralize antigenic and toxic substances
Implementation Method 2
reducing antibody production, and interfering with neurotoxins and autoimmune responses
Data Source
AI summary
An embodiment is a method of preventing, mitigating or treating neurological conditions and diseases that includes administering an effective amount of a medicament comprised of Lactobacillus bulgaricus B-30892 and/or a supernatant resulting from culturing Lactobacillus bulgaricus B-30892 and/or bioactive materials resulting from culturing Lactobacillus bulgaricus B-30892 to a human to prevent, mitigate or treat neurological conditions and diseases.