Lactobacillus Probiotic Composition for Diet Self-Control
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Solution Overview
Problem
Current probiotic compositions for weight management and psychological well-being associated with restrictive diets are limited in efficacy due to variability in individual responses, particularly because they often include prebiotics that affect native microbiota unpredictably, making it difficult to predict their effectiveness across subjects.
Innovation Solution
A probiotic composition comprising specific strains of Lactobacillus bacteria, such as Lactobacillus rhamnosus, administered in controlled amounts to facilitate self-control and alleviate negative psychological effects like hunger, anxiety, and binge eating tendencies during restrictive diets, without the use of prebiotics to minimize individual variability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If prebiotics are added to probiotic compositions to enhance effectiveness, then the composition may show moderate success in improving appetite sensations and eating behaviors, but the effect becomes difficult to predict across subjects due to unpredictable stimulation of native microbiota
Solution Approach 1:
The patent removes prebiotics from the probiotic composition, extracting the problematic element that causes unpredictable effects on native microbiota. This leaves only the probiotic bacteria to provide consistent, predictable effects across subjects without the confounding variable of prebiotic-induced microbiota changes.
Solution Approach 2:
The patent separates the probiotic component from the prebiotic component, treating them as independent elements. By using probiotics alone rather than in combination with prebiotics, the composition achieves consistent effects without the interactive complexity that makes synbiotic effects unpredictable across different individuals.
2Productivity
If synbiotics are used instead of probiotics alone to improve effectiveness, then appetite control may be enhanced, but individual variability in response increases due to host-specific microbiota interactions
Solution Approach 1:
The patent extracts prebiotics from the synbiotic formulation, removing the source of individual variability. By using probiotics alone, the composition achieves consistent effects across subjects while maintaining appetite control effectiveness, eliminating the host-specific microbiota interaction problem.
3Weight of moving object
If restrictive diets are implemented to manage weight, then fat accumulation may be reduced, but negative psychological effects such as hunger, anxiety, and binge eating tendencies increase
Solution Approach 1:
The patent introduces probiotic bacteria as an intermediary substance that mediates between the restrictive diet and the psychological effects. The probiotics modulate the gut-brain axis, reducing negative psychological effects like hunger and anxiety while allowing the restrictive diet to effectively reduce fat accumulation.
Solution Approach 2:
The patent establishes a feedback loop where probiotics influence gut-brain communication to regulate psychological responses to dieting. This feedback mechanism helps manage hunger signals and emotional eating tendencies, making the restrictive diet more psychologically sustainable while maintaining fat loss.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The probiotic composition effectively reduces fat accumulation, improves appetite control, and enhances psychological well-being by modulating eating behaviors and mood-related factors, demonstrating consistent benefits across subjects, even when used in conjunction with dietary interventions.
Implementation Method 1
these dietary changes can also significantly impact the gut microbiota composition and function. Beyond the simple correlation between gut dysbiosis, obesity and metabolic diseases, disruptions of host-microbiota interactions in this context were proposed to directly impair the host's metabolism through production of microbial metabolites.
Implementation Method 2
The gut communicates with the brain in various ways, including the vagus nerve, microbiota-derived neuroactive compounds, enzymes or gut-derived inflammatory signals.
Data Source
AI summary
The present disclosure concerns a probiotic composition comprising an effective amount of a probiotic product and an acceptable carrier. The probiotic composition can be used in favoring wellness and facilitating self-control in a subject who had been on a restrictive diet, is currently on the restrictive diet and/or intends to be on the restrictive diet. The probiotic product comprises at least one of a population of probiotic bacteria from a Lactobacillus genus and/or a microbial component derived from the population of the probiotic bacteria.