Lactococcus Composition for UV-Damaged Skin Moisture and Redness
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Solution Overview
Problem
Existing food materials derived from lactic acid bacteria do not effectively improve skin conditions deteriorated by factors such as ultraviolet light, aging, and stress, and may have side effects when used for prolonged periods.
Innovation Solution
Utilizing Lactococcus lactis subsp. lactis JCM5805 as an active ingredient, either live or dead, in various forms, to improve skin conditions by ingestion, which can be incorporated into food or pharmaceutical products, providing a safe and long-term solution without side effects.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing food materials derived from lactic acid bacteria are used to improve skin conditions, then skin function improvement is achieved, but side effects occur when used for prolonged periods
Solution Approach 1:
The patent changes the strain parameter by specifying Lactococcus lactis subsp. lactis JCM5805, a particular strain isolated from human feces. This specific strain selection resolves the contradiction by ensuring prolonged use safety while maintaining skin improvement effects, as this particular strain has been shown to improve skin conditions without causing side effects during extended usage periods.
2Reliability
If lactic acid bacteria are used to improve skin conditions deteriorated by ultraviolet light, then skin barrier function is improved, but existing food materials do not effectively address UV-induced deterioration
Solution Approach 1:
The patent changes the functional parameter by demonstrating that Lactococcus lactis subsp. lactis JCM5805 specifically addresses UV-induced skin deterioration. The strain improves skin barrier function and reduces erythema caused by ultraviolet light exposure, resolving the contradiction by showing effectiveness against UV damage rather than just general skin improvement.
3Reliability
If lactic acid bacteria are used to improve skin conditions, then skin redness and moisture are improved, but the mechanism for prolonged safety is not established
Solution Approach 1:
The patent changes the temporal parameter by establishing that Lactococcus lactis subsp. lactis JCM5805 can be used continuously for prolonged periods without causing side effects. The strain improves skin redness and moisture content while maintaining safety during extended usage, resolving the contradiction by demonstrating both effectiveness and long-term safety.
Data Source
Figure 1~2B
Figure 3A~4B
AI summary
An object of the present invention is to provide a novel food material effective for improving skin conditions. The present invention provides a composition for use in improving skin conditions, comprising a Lactococcus bacterium as an active ingredient. Examples of the Lactococcus bacterium include Lactococcus lactis. The skin conditions are skin conditions deteriorated by light exposure, such as an increase in skin redness and a decrease in skin moisture content.