LAH169 Hybrid Rice Yield and Chalk Reduction via Two-Line Breeding

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Solution Overview

Problem

The traditional rice breeding process is time-consuming and unpredictable, requiring extensive efforts and resources to develop superior rice cultivars or hybrids, as breeders lack direct control over genetics and face billions of possible genetic combinations, making it challenging to identify and produce genetically superior plants consistently.

Innovation Solution

The development of a novel, high-yielding, early-maturing, non-aromatic conventional long-grain rice hybrid designated 'LAH169' using the two-line breeding method, which includes single-gene converted plants for traits like insect resistance, disease resistance, and enhanced nutritional quality, along with regenerable cells for tissue culture to maintain consistent physiological and morphological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional rice breeding process is used, then breeders can develop rice cultivars or hybrids, but the process is time-consuming and unpredictable with billions of possible genetic combinations

Engineering Contradiction:
Improvepredictability of developing genetically superior plantsVSAvoidtime required for breeding process
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent replaces traditional mechanical breeding methods (manual crossing, selection, and evaluation of billions of genetic combinations) with genetic engineering techniques. Specifically, breeders can directly introduce desired traits through transgenic approaches or gene editing, bypassing the unpredictable mechanical process of traditional hybridization and selection.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent enables direct modification of genetic parameters through biotechnology. Instead of relying on natural genetic recombination over multiple generations, breeders can directly alter specific genes or introduce targeted genetic modifications, changing the fundamental parameters of how genetic improvement is achieved.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If breeders use traditional methods to identify superior plants, then they can select for desired traits, but extensive efforts and resources are required

Engineering Contradiction:
Improveconsistency in producing genetically superior plantsVSAvoidresources required for breeding
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent replaces resource-intensive traditional breeding mechanics with efficient genetic engineering approaches. Instead of maintaining large breeding populations and conducting extensive field trials, breeders can work with smaller, more targeted genetic modifications that require fewer resources while achieving consistent results.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent enables direct copying of desired genetic traits from donor organisms or synthetic constructs into target rice varieties. This eliminates the need to repeatedly develop and test numerous breeding lines, as the proven genetic modifications can be directly replicated across different varieties and populations.

Inventive Principle:
Principle #26Copying

3Ease of manufacture

If breeders lack direct control over genetics, then traditional breeding can proceed, but it is challenging to identify and produce genetically superior plants consistently

Engineering Contradiction:
Improveease of producing rice with desired traitsVSAvoidconsistency of genetic superiority
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent replaces the indirect mechanical process of traditional breeding (where breeders rely on statistical probability and phenotypic selection) with direct genetic control mechanisms. Breeders can now precisely introduce, delete, or modify specific genes to achieve desired traits, providing direct control over the genetic outcome rather than relying on random recombination.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces molecular biology tools and techniques as intermediaries between breeder intent and genetic outcome. These tools (such as CRISPR-Cas9, gene guns, or Agrobacterium-mediated transformation) serve as precise mediators that allow breeders to directly implement genetic changes without the intermediate steps of traditional crossing and selection.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS10834885B1Hybrid rice designated ‘LAH169’
Publication Date: 2020.11.17 BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV & AGRI & MECHANICAL COLLEGE

AI summary

A hybrid rice designated ‘LAH169’ is disclosed.