Laminate with Undercoat Layer for Bacterial Adhesion Suppression
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Solution Overview
Problem
Existing dental compositions and coatings for devices implanted in the human body, such as denture bases, fail to effectively suppress bacterial adhesion, especially in wet environments, leading to peeling off of the coating and reduced performance.
Innovation Solution
A laminate structure comprising a base material with an undercoat layer formed from a polymer containing polymerizable and polar groups, and a cured film using specific compounds represented by Formulas (I), (II), (IV), and (V), with a double bond equivalent of 2000 or less, which enhances adhesion and prevents peeling in wet conditions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a coating layer is formed on a base material using conventional dental composition, then the base material is covered, but the coating layer peels off in wet environments and fails to suppress bacterial adhesion
Solution Approach 1:
The coating is divided into two distinct layers: an undercoat layer formed from a polymer containing both polymerizable groups and polar groups that provides strong adhesion to the base material, and a cured film layer formed from specific compounds (Formulas I, II, IV, V) that provides bacteria adhesion suppression performance. This segmentation allows each layer to specialize in its function without compromising the other.
Solution Approach 2:
The undercoat layer uses a composite polymer structure containing both polymerizable groups (for co-polymerization with the cured film) and polar groups (for adhesion and interaction with bacterial surfaces). The cured film layer uses specific zwitterionic or betaine compounds that create a composite structure with the undercoat, resulting in a multi-functional coating system that simultaneously achieves strong adhesion and bacterial suppression.
2Object-affected harmful factors
If the coating layer is applied to suppress bacterial adhesion, then bacteria adhesion is reduced, but the coating peels off in wet environments
Solution Approach 1:
The undercoat layer is applied first to the base material before applying the cured film layer. The undercoat layer performs preliminary adhesion to the base material and provides a stable foundation that prevents subsequent peeling of the entire coating system, even in wet environments. This preliminary action ensures long-term stability.
Solution Approach 2:
The undercoat layer acts as an intermediary between the base material and the cured film layer. It contains both polymerizable groups (that co-polymerize with the cured film) and polar groups (that interact with the base material and provide adhesion). This intermediary structure mediates the connection between the base material and the bacterial-suppressing cured film, ensuring stable integration.
3Device complexity
If a single-layer coating is used, then the structure is simple, but it cannot simultaneously achieve strong adhesion and bacteria adhesion suppression
Solution Approach 1:
The coating system is segmented into two functional layers: the undercoat layer (polymer with polymerizable and polar groups) handles adhesion to the base material, while the cured film layer (specific compounds I, II, IV, V) handles bacterial adhesion suppression. This segmentation enables each layer to optimize its function, achieving high reliability despite increased structural complexity.
Solution Approach 2:
The undercoat layer polymer contains both polymerizable groups (enabling co-polymerization with the cured film) and polar groups (enabling adhesion to base material and interaction with bacteria). This multi-functionality in the undercoat layer, combined with the specialized cured film layer, creates a universal coating system that simultaneously achieves adhesion and bacterial suppression.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The laminate demonstrates excellent bacteria adhesion suppression performance, maintaining adhesiveness and preventing peeling even in wet environments, effectively reducing bacterial adhesion from Candida and periodontal bacteria.
Implementation Method 1
an undercoat layer formed of an undercoat layer forming composition containing a polymer containing a repeating unit containing a polymerizable group
Implementation Method 2
a repeating unit containing a polar group; maintaining adhesiveness and preventing peeling even in wet environments
Implementation Method 3
a cured film formed of a curable composition containing at least one compound selected from the group consisting of a compound represented by Formula (I), a compound represented by Formula (II), a compound represented by Formula (IV), and a compound represented by Formula (V)
Data Source
AI summary
The present invention provides a laminate having excellent bacteria adhesion suppression performance. The present invention also provides a kit and a method for producing a laminate. A laminate according to the present invention includes a base material, an undercoat layer formed of an undercoat layer forming composition containing a polymer containing a repeating unit containing a polymerizable group and a repeating unit containing a polar group, and a cured film formed of a curable composition containing at least one compound selected from the group consisting of a compound represented by Formula (I), a compound represented by Formula (II), a compound represented by Formula (IV), and a compound represented by Formula (V) in this order.