Portable Laser Biosensor Combining Absorption and Fluorescence Spectroscopy

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

There is a need for a portable, handheld device that can simultaneously perform molecular absorption spectrophotometry and molecular fluorescence spectrophotometry for efficient field testing of substances within a fluid sample, as existing technologies do not offer a combined solution for rapid and accurate analysis.

Innovation Solution

A portable, modular biosensor that combines molecular absorption spectrophotometry and molecular fluorescence spectrophotometry using a laser-based system, featuring a radiation emitting module, sample cell module, absorption detector, fluorescence detector, and processor to provide both absorption and fluorescence spectral data, allowing for rapid and accurate analysis of substances.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a portable biosensor combines both molecular absorption spectrophotometry and molecular fluorescence spectrophotometry in a single device, then measurement precision and selectivity are improved, but device complexity increases

Engineering Contradiction:
Improvedetection accuracyVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines molecular absorption spectrophotometry (MAS) and molecular fluorescence spectrophotometry (MFS) into a single portable biosensor device, integrating both measurement capabilities to provide comprehensive substance detection with improved precision and selectivity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The biosensor is designed as a multi-functional device that can perform both absorption and fluorescence measurements simultaneously, allowing it to detect various substances using different spectroscopic methods within one universal platform

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Ease of operation

If the biosensor is designed to be portable and handheld, then ease of operation is improved, but the device size and volume increase

Engineering Contradiction:
ImproveportabilityVSAvoiddevice volume
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The biosensor is divided into modular components including a radiation emitting module, sample cell module, detection modules, and display module that can be independently configured and assembled, enabling portable design while maintaining full functionality

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent replaces traditional mechanical spectrophotometer components with laser-based radiation emission and electronic detection systems, significantly reducing the device size while maintaining measurement capabilities for portable operation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The biosensor enables rapid and accurate detection of substances by providing improved selectivity and sensitivity through combined absorption and fluorescence measurements, suitable for various applications including military, food, and health industries, with a compact and user-friendly design.

Implementation Method 1

a light source received within the radiation emitting module housing and configured to generate excitation energy, illustratively a laser beam

Methodology Applied
Scientific EffectLaser: Laser

Implementation Method 2

An absorption detector is configured to detect emission intensity produced by the electromagnetic radiation passing through the solution in the sample cell chamber and produce absorption spectral data in response thereto

Methodology Applied
Scientific EffectMolecular absorption spectrophotometry: Absorption Spectroscopy

Implementation Method 3

A fluorescence detector is configured to detect molecular emissions produced by the laser excited molecules as the laser beam passes through the solution in the sample cell chamber and produces fluorescence spectral data in response thereto

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS20180217060A1Portable laser biosensor
Publication Date: 2018.08.02 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY
  • US20180217060A1 patent drawing
  • US20180217060A1 patent drawing
  • US20180217060A1 patent drawing

AI summary

A hand-held laser based biosensor including modular components, combining absorption spectrophotometry and molecular fluorescence spectrophotometry, and including a sample cell module having an improved absorption path length.