Laser Catheter Pulsating Beam Vessel Wall Ablation

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Solution Overview

Problem

Existing laser catheters for bypass surgery, such as the ELANA technique, face challenges in effectively cutting through the vessel wall without causing unnecessary damage or incomplete removal of the 'flap' during ETS-anastomosis, leading to potential obstruction of blood flow.

Innovation Solution

A laser catheter system with a fibre bundle of optical fibres emitting a pulsating ultraviolet light beam at an ablation power of at least 40 mJ/mm² per pulse, controlled by an excimer laser and a timing device for predefined emitting and break intervals, ensuring precise cutting of the vessel wall while preventing cutting through both sides of the vessel.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the laser catheter uses higher ablation power to cut through the vessel wall more effectively, then the cutting effectiveness is improved, but there is a risk of cutting through both sides of the vessel causing damage

Engineering Contradiction:
Improvecutting effectivenessVSAvoiddamage to opposite vessel wall
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The laser catheter emits pulsating light beams with a duty cycle of 10-50%, delivering high ablation power during pulse intervals while allowing cooling and tissue recovery between pulses. This periodic action enables effective cutting at 40-100 mJ/mm² peak power without causing excessive thermal damage to the opposite vessel wall, as the intermittent nature of the pulses allows heat dissipation and prevents continuous thermal accumulation that would lead to through-cutting.

Inventive Principle:
Principle #19Periodic action

2Manufacturing precision

If the laser catheter emits continuous light beam to ensure complete removal of the flap, then the completeness of flap removal is improved, but the risk of heating and burning damage to surrounding tissue increases

Engineering Contradiction:
Improvecompleteness of flap removalVSAvoidburning damage to surrounding tissue
Core Design Contradiction:
Manufacturing precisionVSObject-generated harmful factors

Solution Approach 1:

The system uses pulsating laser beams with duty cycles of 10-50% to deliver high ablation energy in intermittent bursts rather than continuous exposure. This periodic delivery allows the tissue to cool between pulses, preventing thermal accumulation and burning damage to surrounding healthy tissue while still achieving complete flap removal through cumulative ablation effect over multiple pulses.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The laser system dynamically adjusts the ablation power parameter to 40-100 mJ/mm² during pulse intervals and reduces it to near-zero during break intervals. This parameter modulation enables precise control of the ablation process, achieving complete flap removal through controlled cumulative energy delivery while preventing thermal damage by periodically reducing the energy input below the damage threshold.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The increased ablation power and pulsating frequency enhance the effectiveness of cutting away the flap without causing damage to the opposite vessel wall, ensuring complete removal and minimizing the risk of blood flow obstruction.

Implementation Method 1

a laser apparatus, comprising one or more lasers for supplying light to the optical fibres

Methodology Applied
Scientific EffectLaser: Laser

Implementation Method 2

a fibre bundle of optical fibres having distal ends defining a light emitting surface for emitting a light beam

Methodology Applied
Scientific EffectOptical fibre transmission: Optical Fibre

Implementation Method 3

emitting a pulsating light beam with an ablation power of at least 40 mJ/mm²

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 4

The tubular bundle of the laser light beam ablates a circle into the wall of the target vessel

Methodology Applied
Scientific EffectAblation: Ablation

Data Source

PatentEP2475321B1A laser catheter system for bypass surgery
Publication Date: 2015.03.11 CORVASCO MEDICAL
  • EP2475321B1 patent drawingFigure 1a~1b
  • EP2475321B1 patent drawingFigure 2a~2b
  • EP2475321B1 patent drawingFigure 2c~2d

AI summary

A catheter system is provided comprising a laser catheter with a fibre bundle of optical fibres emitting a light beam in the distal direction of the catheter and a laser apparatus, comprising one or more lasers for supplying light to the optical fibres. The catheter system is preset or adjusted for emitting a pulsating light beam with an ablation power of at least 40 mJ/mm2 per pulse at the location of a light emitting surface. A method for preparing such a catheter system is provided comprising the step of a) measuring said ablation power at the location of the light emitting surface; b) comparing the measured ablation power with a predefined power value requirement; c) in case the measured ablation power is different from the predefined power value requirement, adjusting the ablation power of the pulsating light beam to meet the predefined power value requirement.