Liquid Crystal Polymer Neural Implant Electrode Array Manufacturing

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Solution Overview

Problem

Conventional neural implants face challenges in manufacturing due to high skill requirements, high costs, low yield, and limitations in flexibility and optical integration, particularly with the use of metal wire electrodes and titanium packages, which result in issues like disconnection, blockage, and poor optical characteristics.

Innovation Solution

A method for manufacturing a liquid crystal polymer-based neural implant using a semiconductor process with a seed layer, plating mold, and thermocompression, along with laser etching and plasma treatment, to create a multi-channel electrode array and sealed package with improved adhesion and flexibility, and integration of optical windows for enhanced performance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If high pressure is applied during thermocompression process, then adhesion between layers is improved, but metal pattern disconnection occurs

Engineering Contradiction:
Improveadhesion between layersVSAvoidmetal pattern continuity
Core Design Contradiction:
StrengthVSReliability

Solution Approach 1:

The patent applies preliminary action by forming a recessed cavity in the liquid crystal polymer substrate before thermocompression bonding. This cavity accommodates the metal pattern, providing a stress-free zone that prevents disconnection during high-pressure bonding while maintaining strong adhesion between layers.

Inventive Principle:
Principle #10Preliminary action

2Ease of manufacture

If conventional manual manufacturing method is used, then manufacturing flexibility is maintained, but manufacturing cost increases and yield decreases

Engineering Contradiction:
Improvemanufacturing flexibilityVSAvoidmanufacturing yield
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent replaces manual mechanical manufacturing processes with automated semiconductor fabrication processes. The electrode pattern is formed using photolithography and sputtering techniques instead of manual wire manipulation, enabling automated high-volume production with improved yield while maintaining design flexibility through programmable patterning.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of operation

If hole is made in advance for electrode site, then alignment is facilitated, but hole becomes narrower or blocked during thermocompression

Engineering Contradiction:
Improvealignment easeVSAvoidelectrode site openness
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent forms the recessed cavity in advance before bonding, but unlike conventional pre-made holes, this cavity is designed with sufficient width and depth to accommodate the metal pattern while preventing blockage during thermocompression. The cavity serves as a stress-relief zone that maintains electrode site openness.

Inventive Principle:
Principle #10Preliminary action

4Strength

If minimum thickness of liquid crystal polymer film is 25 μm, then structural integrity is maintained, but electrode flexibility and optical characteristics deteriorate

Engineering Contradiction:
Improvestructural integrityVSAvoidelectrode flexibility
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The patent segments the liquid crystal polymer structure into two distinct components: a thin substrate (5-20 μm) that provides flexibility and optical characteristics, and a separately bonded cover layer that provides structural integrity and protection. This segmentation allows each layer to be optimized for its specific function.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The recessed cavity is formed preliminarily in the thin substrate before bonding, providing structural support at critical locations without requiring the entire substrate to be thick. This allows the substrate to maintain overall thinness for flexibility while having localized reinforcement where needed.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach increases yield and reduces costs while enabling the production of flexible electrodes with high channel density and improved optical characteristics, addressing issues of disconnection, blockage, and optical integration in conventional methods.

Implementation Method 1

a liquid crystal polymer cover layer with a site window 108 formed therein is adhered to a front surface of the liquid crystal polymer substrate 102 with the electrode 104 formed therein

Methodology Applied
Scientific EffectThermocompression:

Implementation Method 2

an electrode site (a part in which a metal is exposed to interface with a nerve cell) at a liquid crystal polymer-based electrode is formed by making a hole corresponding to a site window at a liquid crystal polymer cover layer using a laser

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 3

since a thermocompression process is performed using a heating press and the like

Methodology Applied
Scientific EffectPhase transition: Phase Change

Data Source

PatentUS10500393B2Liquid crystal polymer-based electrode array and package for neural implant, and manufacturing method therefor
Publication Date: 2019.12.10 SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
  • US10500393B2 patent drawing
  • US10500393B2 patent drawing
  • US10500393B2 patent drawing

AI summary

A method for manufacturing a liquid crystal polymer-based electrode array for a neural implant, according to the present invention, can comprise the steps of: forming a seed layer on a liquid crystal polymer substrate; forming a plating mold having a pattern selectively exposing a part of the upper part of the seed layer; plating an electrode material on the exposed seed layer by using the plating mold as a plating barrier layer; forming an electrode by removing the plating mold and the seed layer therebelow; embedding the electrode by compressing a liquid crystal polymer cover layer on the electrode; and forming an electrode site exposing the upper part of the electrode by selectively removing a part of the liquid crystal polymer cover layer.