Lead Body Control Unit for Precise Neurostimulation

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Solution Overview

Problem

Conventional systems for neurostimulation and neuromodulation therapies face limitations in precisely delivering electrical signals to targeted areas due to a limited number of transducer contacts, leading to potential over-stimulation of non-targeted areas and side effects such as speech and memory issues.

Innovation Solution

The integration of a control unit within the electrical lead body, positioned close to transducer contacts, allows for a greater number of output wires and transducer contacts, enabling precise signal delivery by amplifying the number of filaments that can be used without increasing the lead diameter, thus accommodating more transducer contacts for finer control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the number of transducer contacts is increased to improve signal delivery precision, then the precision of signal delivery to targeted areas is improved, but the lead diameter must be increased which is not acceptable

Engineering Contradiction:
Improveprecision of signal deliveryVSAvoidlead diameter
Core Design Contradiction:
Measurement precisionVSLength of stationary object

Solution Approach 1:

The control unit is positioned within the lead body, nesting additional functional components inside the existing lead structure. This allows the lead to accommodate more transducer contacts (up to 64) without increasing the outer diameter, as the control unit and additional wiring are integrated within the existing lead body volume.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The control unit enables multiplexing of signals, allowing multiple transducer contacts to be controlled through fewer input wires. This dimensional transformation in signal routing (from one-to-one wiring to many-to-one multiplexed control) allows precision delivery to multiple contacts without proportionally increasing lead complexity or diameter.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Object-affected harmful factors

If more transducer contacts are used to reduce over-stimulation of non-targeted areas, then side effects are reduced, but the device complexity increases

Engineering Contradiction:
Improveside effects from over-stimulationVSAvoiddevice complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The control unit acts as an intermediary between the implantable device and the transducer contacts. It receives signals from the implantable device, processes them through multiplexing, and delivers precise signals to specific transducer contacts. This intermediary function enables precise control of multiple contacts while keeping the implantable device itself relatively simple.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The control unit dynamically changes signal parameters (which transducer contacts are active, signal timing, signal amplitude) based on therapeutic needs. This parameter control allows selective stimulation of targeted areas while avoiding over-stimulation of non-targeted areas, reducing side effects without requiring physical complexity in the implantable device.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP2964321B1A distributed neuro-modulation system with auxiliary stimulation-recording control units
Publication Date: 2020.02.26 THE CHARLES STARK DRAPER LABORATORY INC
  • EP2964321B1 patent drawingFigure 1
  • EP2964321B1 patent drawingFigure 2A
  • EP2964321B1 patent drawingFigure 2B

AI summary

Systems and methods for modulating a physiological process are provided to enable precise delivery of signals to a predetermined treatment site. The systems may comprise an implantable device and an electrical lead body. The electrical lead body may comprise a plurality of transducer contacts in close proximity to an end of the electrical lead body, and a control unit positioned within the lead body in close proximity to the plurality of transducer contacts.