Multi-chamber Leadless Pacemaker Synchronization via Inter-device Communication

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Solution Overview

Problem

Existing multi-device systems for managing heart activity face challenges in coordinating synchronized contractions across heart chambers, particularly in detecting abnormal atrial contractions and delivering appropriate electrical stimulation to prevent dangerous heart rates.

Innovation Solution

The system employs multiple implanted devices, including pacemakers and sensors, that communicate cardiac events and electrical stimulation between chambers to ensure synchronized contractions, using features like tracking and non-tracking modes, maximum tracking rate intervals, and post-ventricular atrial refractory periods to manage arrhythmias.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple implanted devices are used to manage heart activity across chambers, then coordination of synchronized contractions is improved, but device complexity increases

Engineering Contradiction:
Improvecoordination of synchronized contractionsVSAvoidmultiple implanted devices
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system divides the heart management function into multiple independent implantable devices, each responsible for specific chambers (atria and ventricles). Each device independently monitors and controls its assigned chamber, enabling synchronized multi-chamber coordination through segmented functional distribution rather than a single complex device

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Multiple implantable devices communicate and coordinate through a hierarchical structure where devices are nested within the overall system architecture. The devices exchange data and commands through defined communication protocols, allowing complex multi-chamber management to be achieved through coordinated simpler components

Inventive Principle:
Principle #7Nested doll (Nesting)

2Reliability

If tracking mode is used to pace ventricle based on atrial contraction, then synchronized contractions are achieved, but dangerous high heart rates may occur

Engineering Contradiction:
Improvesynchronized contractionsVSAvoiddangerous high heart rates
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system continuously monitors atrial contraction rates and uses this feedback to dynamically adjust ventricular pacing behavior. When atrial rate exceeds safe thresholds, the feedback mechanism triggers a mode switch from tracking to non-tracking, preventing dangerous high heart rates while maintaining synchronized contractions at normal rates

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The pacing mode is made dynamic rather than static, allowing automatic transition between tracking and non-tracking modes based on real-time heart rate conditions. This dynamic adaptation enables the system to optimize synchronized contractions during normal conditions while preventing harmful effects during tachycardia

Inventive Principle:
Principle #15Dynamics

3Object-affected harmful factors

If maximum tracking rate interval is set to limit ventricular rate, then dangerous heart rates are prevented, but synchronized contractions may be restricted

Engineering Contradiction:
Improvedangerous heart ratesVSAvoidsynchronized contractions
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The tracking rate limit is implemented dynamically with automatic mode switching. When the maximum tracking rate interval is reached, the system automatically transitions from tracking mode to non-tracking mode, preventing dangerous heart rates while preserving the ability to achieve synchronized contractions when rates are within safe limits

Inventive Principle:
Principle #15Dynamics

Data Source

PatentEP3104935B1Multi-chamber leadless pacemaker system with inter-device communication
Publication Date: 2020.06.24 CARDIAC PACEMAKERS INC
  • EP3104935B1 patent drawingFigure 1
  • EP3104935B1 patent drawingFigure 2
  • EP3104935B1 patent drawingFigure 3

AI summary

Systems and methods for switching modes in a multi-device medical system. In one example, a first leadless cardiac pacemaker (LCP) may be implantable at a ventricular site, and a second leadless cardiac pacemaker (LCP) may be implantable at an atrial site and configured to sensing atrial contractions. The first LCP and the second LCP may be configured to be communicatively coupled such that the first LCP and the second LCP can deliver pacing therapy to the ventricular site in a tracking mode. The first LCP and/or the second LCP may additionally be configured to deliver pacing therapy to the ventricular site in a non-tracking mode if an interval between atrial contractions sensed by the second LCP becomes shorter than a threshold duration.