Leadless Pacemaker Multi-Sensor Atrial Event Detection

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Solution Overview

Problem

Leadless pacemakers face challenges in reliably detecting atrial activity signals for ventricular pacing due to weak signal reception from the ventricle, which affects AV synchrony and hemodynamic benefits.

Innovation Solution

A leadless pacemaker device with multiple sensor arrangements that switch between different sensing states to detect atrial events using electrical and mechanical signals, employing processing circuitry to analyze characteristic values and switch between primary and secondary sensors to ensure reliable atrial tracking.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a leadless pacemaker is placed in the ventricle to avoid lead-related risks, then patient safety is improved, but the ability to reliably detect atrial activity signals deteriorates

Engineering Contradiction:
Improvepatient safetyVSAvoidatrial activity signal detection
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent combines multiple sensing modalities (electrical, mechanical, acoustic) into a single integrated sensing system within the ventricular pacemaker. This merging of different sensing approaches allows the device to detect atrial activity through multiple pathways, compensating for the weak electrical signals received in the ventricle while maintaining the leadless design benefits.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent introduces mechanical and acoustic sensors as intermediary detection methods. Instead of relying solely on direct electrical signal transmission from the atrium through the ventricle, the system uses mechanical wall motion and acoustic signals as intermediaries that can be detected more reliably in the ventricular location, thereby bridging the detection gap.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If multiple sensor arrangements are added to improve atrial event detection, then detection reliability is improved, but device complexity increases

Engineering Contradiction:
Improveatrial event detection reliabilityVSAvoidsensor arrangement complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent designs the multiple sensor arrangements to serve multiple functions. The electrical sensors detect both atrial and ventricular electrical activity, the mechanical sensors detect both atrial wall motion and ventricular contraction, and the acoustic sensors capture heart sounds from multiple phases. This multi-functionality reduces the need for separate dedicated sensors for each detection task, thereby limiting complexity growth.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The processing circuitry automatically analyzes signals from multiple sensor arrangements and self-determines the most reliable detection method based on signal quality. The system performs self-validation by comparing signals across different modalities and automatically selects the optimal sensing approach, reducing the need for complex external control mechanisms.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables continuous and adaptive ventricular pacing with improved reliability in detecting atrial events, maintaining AV synchrony and reducing the risk of pacing mode switching errors.

Implementation Method 1

a first sensor arrangement (11, 13) configured to receive a first sense signal

Methodology Applied
Scientific EffectElectrical signal detection: Conduction (electrical)

Implementation Method 2

a second sensor arrangement (16-18) configured to receive a second sense signal

Methodology Applied
Scientific EffectMechanical signal detection: Accelerometer

Data Source

PatentEP3789081B1Leadless cardiac pacemaker device configured to provide intra-cardiac pacing
Publication Date: 2023.08.23 BIOTRONIK SE & CO KG
  • EP3789081B1 patent drawingFigure 1
  • EP3789081B1 patent drawingFigure 2~3
  • EP3789081B1 patent drawingFigure 4~6

AI summary

A leadless pacemaker device (1) configured to provide for an intra-cardiac pacing comprises a processing circuitry (15) configured to generate ventricular pacing signals for stimulating ventricular activity at a ventricular pacing rate, a first sensor arrangement configured to receive a first sense signal, and a second sensor arrangement configured to receive a second sense signal. The processing circuitry (15) is configured to derive, in a first sensing state, atrial events (As) from the first sense signal for controlling the ventricular pacing rate based on said atrial events (As). The processing circuitry (15) is further configured to switch, based on at least one switching criterion, from the first sensing state to a second sensing state in which the processing circuitry (15) is configured to derive atrial events (As) from the second sense signal.