Pharmaceutical Package Leaflet Perforation and Adhesive Bonding

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Solution Overview

Problem

The challenge lies in creating a method to securely, compactly, and easily insert multi-part patient information into pharmaceutical product packaging while ensuring high safety and ease of handling, as existing solutions face issues with misassembly, space constraints, and mechanical insertion difficulties.

Innovation Solution

A method involving a single printed sheet with longitudinal and transverse folds, adhesive application, and perforations to create detachable book-like parts that can be compactly folded and securely inserted, with additional steps for further compaction and closure using an adhesive label, ensuring secure and user-friendly handling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Volume of moving object

If a single printed sheet is folded multiple times to create a compact package insert, then the compactness and space utilization improve, but the ease of handling and user comprehension deteriorate due to confusion and difficulty in unfolding

Engineering Contradiction:
Improvecompactness of package insertVSAvoidease of handling by user
Core Design Contradiction:
Volume of moving objectVSEase of operation

Solution Approach 1:

The printed sheet is divided into multiple detachable book-like parts through perforations, allowing users to separate and handle individual sections easily while maintaining compactness when assembled. The perforations enable clean separation without damaging the overall structure.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent transforms the traditional flat folded insert into a three-dimensional book-like structure with multiple detachable parts. This dimensional transformation allows the insert to be compact when assembled but easily separable and handleable when opened, resolving the contradiction between compactness and ease of handling.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If intensive monitoring such as camera monitoring is used to prevent misassembly of printed sheets, then the reliability improves, but the device complexity and manufacturing cost increase

Engineering Contradiction:
Improveprevention of misassemblyVSAvoidcomplexity of monitoring system
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The printed sheet design inherently prevents misassembly through its self-explanatory book-like structure with detachable parts. The perforations and adhesive bonds create a structure that naturally guides correct assembly without requiring external monitoring systems, making the system self-checking and foolproof.

Inventive Principle:
Principle #25Self-service

3Quantity of substance

If multiple information media are attached to pharmaceutical products to meet regulatory requirements, then the completeness of information improves, but the ease of insertion into product packaging deteriorates due to space constraints and mechanical difficulties

Engineering Contradiction:
Improveamount of information providedVSAvoidease of mechanical insertion
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

Multiple information media are merged into a single integrated printed sheet that is then folded into book-like parts. This consolidation allows all required information to be provided in one compact unit that can be easily inserted into product packaging as a single item, eliminating the difficulties of handling multiple separate media.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The book-like parts with detachable sections allow information to be nested within a compact structure. The perforated sections can be separated and nested within each other or within the product packaging, maximizing space utilization while maintaining ease of insertion.

Inventive Principle:
Principle #7Nested doll (Nesting)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method ensures secure assembly, compact packaging, and easy handling of multi-part information, reducing the risk of misassembly and space constraints, while allowing for efficient production and user-friendly separation of information, enhancing product safety and usability.

Implementation Method 1

applying at least two adhesive tracks running in the longitudinal direction or at least one adhesive area on one or both sides of the printed sheet; making at least one longitudinal folds in such a way that the interaction of the adhesive tracks or the at least one adhesive area forms adhesive bonds connecting at least two printed sheet areas placed one on top of the other

Methodology Applied
Scientific EffectAdhesion: Adhesive

Data Source

PatentEP2813369B1Method for producing a printed product, in particular a package insert, and printed product
Publication Date: 2016.07.20 BAHREN WALTER
  • EP2813369B1 patent drawingFigure 1a~1c
  • EP2813369B1 patent drawingFigure 2a~2d
  • EP2813369B1 patent drawingFigure 3a~3b

AI summary

The invention relates to a method for producing a printed product, in particular a multi-part package leaflet for a pharmaceutical product, from a single printed sheet (40) having a longitudinal side and a transverse side, comprising the steps of: applying adhesive traces (44a-d) to one or both sides of the printed sheet (40), making one or more longitudinal folds such that, by the interaction of the adhesive traces (44a-d), at least four superimposed printed sheet areas are bonded together;The process involves introducing at least two perforations (42a, 42b) into the printed sheet (40) in the longitudinal direction, applying further adhesive (48a, 48b), making a transverse fold and gluing the two transversely folded parts together in such a way that the number of pages of the printed product resulting from the final product is doubled, and trimming the printed sheet (40) thus processed, wherein the correspondingly processed product in a long state has at least two consecutive parts (46a, 46b) which are separably connected to each other at at least one perforation (54), wherein each part (46a, 46b) is bound in a book-like manner by the gluing in the detached state. To achieve a packaging state, this product in its long state is then folded crosswise – possibly several times – and provided with a perforated adhesive label (48) so that the product can be inserted into a folding carton packaging without interference.