Lensless Near-Field Microscopy for Pixel-Limited Resolution

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Solution Overview

Problem

Conventional optical microscopy is limited by the diffraction limit, which restricts resolution to several hundred nanometers, making it difficult to achieve high-resolution imaging of specimens without the use of expensive and complex optical elements or computational corrections.

Innovation Solution

An imaging device with a high-resolution photosensitive array and supporting circuitry that captures images without lenses or computational corrections, achieving pixel-limited resolution by bringing specimens close to the photosensitive surface, thereby overcoming the diffraction limit.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional optical microscopy is used, then imaging can be performed with standard equipment, but resolution is limited to several hundred nanometers by the diffraction limit

Engineering Contradiction:
Improveimaging resolutionVSAvoidoptical system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and removes the lens component from the optical system entirely. By placing the photosensitive array directly against the specimen, the system eliminates the intermediate optical elements (lenses, mirrors, etc.) that cause diffraction and complexity, achieving super-resolution imaging through direct near-field detection

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a photosensitive array as a direct intermediary between the light source and specimen. This array operates in the near-field region without requiring traditional optical lenses, allowing resolution to be determined by pixel size rather than diffraction limits

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If high-resolution imaging is achieved using standard optical microscopy, then expensive and complex optical elements or computational corrections are required, but this increases device complexity and cost

Engineering Contradiction:
Improveimaging resolutionVSAvoidoptical elements and computational corrections
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent removes expensive and complex optical elements (such as high-NA lenses, confocal apertures, and specialized illumination systems) from the imaging system. By operating in direct contact mode with a photosensitive array, it achieves high resolution without these costly components

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system uses the pixel array itself to define the resolution limit through its physical pixel size, eliminating the need for computational corrections or complex optical elements. The imaging system serves itself by using simple geometric constraints rather than expensive auxiliary systems

Inventive Principle:
Principle #25Self-service

3Measurement precision

If the photosensitive array is positioned close to the specimen, then pixel-limited resolution is achieved without diffraction limits, but the working distance is reduced

Engineering Contradiction:
ImproveresolutionVSAvoidworking distance
Core Design Contradiction:
Measurement precisionVSLength of moving object

Solution Approach 1:

The patent transitions from far-field optical imaging to near-field imaging by changing the spatial dimension and scale of operation. By operating at distances comparable to pixel dimensions rather than optical focal lengths, the system achieves resolution determined by pixel size rather than diffraction

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The imaging device achieves high-resolution images comparable to standard lens-based optical microscopes without the need for lenses or computational corrections, allowing for imaging of specimens at resolutions limited by the pixel size, rather than the diffraction limit.

Implementation Method 1

an imaging device has a photosensitive array of pixels

Methodology Applied
Scientific EffectPhotoelectric Effect: Photoelectric Effect

Data Source

PatentUS20240385212A1Microscopy imaging
Publication Date: 2024.11.21 ALENTIC MICROSCI
  • US20240385212A1 patent drawing
  • US20240385212A1 patent drawing
  • US20240385212A1 patent drawing

AI summary

Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.