3D Lesion Localization Using Pre-Captured Examination Images
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Solution Overview
Problem
Non-angulating biopsy devices face challenges in determining the 3D coordinates of a lesion for accurate biopsy, as they lack the rotational degree of freedom to provide depth location information, leading to cumbersome and painful procedures for patients.
Innovation Solution
The method involves analyzing pre-existing examination images from initial screening to estimate the missing Z-axis location of the lesion, eliminating the need for additional imaging with the biopsy needle inserted, and using these images to determine the 3D coordinates of the lesion for biopsy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If a non-angulating biopsy device is used, then the device structure is simpler and easier to manufacture, but the ability to determine the Z-axis (depth) location of the lesion is lost
Solution Approach 1:
The system performs preliminary imaging actions by capturing the lesion in examination images at known angles before the biopsy procedure. These pre-captured images contain the depth information needed to calculate 3D coordinates, eliminating the need for the biopsy device to have angulation capability. The coordinates are then used to guide the biopsy needle accurately.
Solution Approach 2:
The system introduces an intermediary computational process that uses the known geometry of the examination device and the 2D coordinates from examination images to calculate the 3D coordinates of the lesion. This computational intermediary bridges the gap between the simplified non-angulating biopsy device and the requirement for accurate 3D lesion localization.
2Measurement precision
If additional imaging with biopsy needle insertion is performed, then the Z-axis location of the lesion can be determined, but the procedure becomes more cumbersome and painful for the patient
Solution Approach 1:
The system performs the imaging action preliminarily during the examination phase before the biopsy procedure. The examination images capture the lesion at known angles and positions, storing the depth information in advance. During the actual biopsy, only a single view image is needed from the biopsy device, avoiding repeated needle insertions and reducing patient discomfort.
Solution Approach 2:
The system uses copies of the examination images (which were taken with the lesion visible but without the biopsy needle) to determine the 3D coordinates. Instead of requiring new images with the needle inserted, the system processes existing image copies along with the known device geometry to calculate the precise lesion location.
3Measurement precision
If multiple views are collected with the biopsy device, then the 3D coordinates of the lesion can be determined, but the procedure time increases
Solution Approach 1:
The system performs the multi-view imaging action preliminarily during the examination phase, not during the biopsy procedure. The examination images captured at different angles contain all the spatial information needed. During the biopsy, only a single view is required from the biopsy device, significantly reducing the time needed for coordinate determination while maintaining accuracy.
Solution Approach 2:
The examination device serves multiple functions: it performs both the initial diagnostic imaging and provides the spatial data needed for biopsy guidance. By using the same device for both purposes and leveraging its known geometry, the system eliminates the need for separate multi-view imaging during the biopsy procedure.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for accurate determination of the 3D location of the lesion using a single view from the biopsy device, reducing patient discomfort and procedural complexity, while maintaining the accuracy of the biopsy.
Implementation Method 1
The examination device emits energy or radiation (x-rays) from an x-ray tube towards through the patient's anatomy, which is then detected by an x-ray detector positioned on the opposite side of the anatomy
Data Source
AI summary
A system for collecting a biopsy of a lesion within a patient using examination images previously collected from an examination device. An x-ray detector detects energy after passing through the patient. A compression paddle compresses the patient. A processing system generates a biopsy image based on the energy detected by the x-ray detector, accesses the examination images previously collected, and analyzes, while the patient remains compressed, the biopsy image to determine a measured x-coordinate and a measured y-coordinate of the lesion along X and Y axes, respectively. The examination images are analyzed to determine a calculated z-coordinate of the lesion along the Z axis. The location of the lesion along the X, Y, and Z axes is determined based on the measured x-coordinate and measured y-coordinate from the biopsy image and the calculated z-coordinate from examination images. The biopsy may be performed while the patient remains compressed.