Lesion Prediction Model for Early Radiological Detection

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Solution Overview

Problem

Current radiological imaging methods rely on visual detection of lesions by radiologists, which often occurs after lesions have grown sufficiently large, leading to delayed detection and potentially more intensive and harmful treatments.

Innovation Solution

A method involving the use of a processor to train a model using pre-lesion and post-lesion images to predict the location of future lesions, allowing for early detection and localization through comparison of regions of interest in images.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If conventional visual detection methods are used, then the detection process is simple and straightforward, but lesion detection is delayed until lesions become sufficiently large to be visible

Engineering Contradiction:
Improvedetection delayVSAvoiddetection system complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The system performs preliminary analysis of radiological images to identify subtle features and patterns that precede visible lesion formation. By analyzing images before lesions become visually detectable and comparing them to subsequent images where lesions are confirmed, the system predicts future lesion locations, enabling early intervention before the lesions grow to a visible size.

Inventive Principle:
Principle #10Preliminary action

2Loss of time

If more frequent patient exams are conducted, then earlier detection of lesions may be enabled, but the cost and burden on patients increases

Engineering Contradiction:
Improvedetection timingVSAvoidnumber of exams
Core Design Contradiction:
Loss of timeVSQuantity of substance

Solution Approach 1:

The system replaces the mechanical approach of frequent physical exams with an automated computational analysis system. The processor analyzes existing radiological images using trained models to predict lesion development, eliminating the need for more frequent imaging exams while achieving the same early detection goal.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Object-affected harmful factors

If lesions are detected later, then the detection process remains simple, but more intensive and harmful treatments are required

Engineering Contradiction:
Improvetreatment intensityVSAvoidlesion size measurement
Core Design Contradiction:
Object-affected harmful factorsVSMeasurement precision

Solution Approach 1:

The system performs preliminary detection of sub-visual lesion indicators before they develop into visible lesions requiring intensive treatment. By predicting lesion locations in advance, the system enables early intervention with milder treatments, preventing the progression to stages where aggressive therapies are necessary.

Inventive Principle:
Principle #10Preliminary action

4Reliability

If a model is trained to predict lesion locations, then early detection is enabled, but the system complexity increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system performs preliminary training using paired radiological images - images taken before lesion appearance and corresponding images taken after lesions become visible. The processor learns to identify precursors to lesion formation by comparing these paired images, enabling reliable prediction of future lesion locations while maintaining a manageable system architecture.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12340512B2Methods and systems for early detection and localization of a lesion
Publication Date: 2025.06.24 GE PRECISION HEALTHCARE LLC
  • US12340512B2 patent drawing
  • US12340512B2 patent drawing
  • US12340512B2 patent drawing

AI summary

Various methods and systems are provided for identifying future occurrences of lesions in a patient. In one example, a method includes feeding first images collected from one or more patients prior to appearance of lesions and second images collected from the one or more patients after appearance of the lesions to a processor to train a model to predict a location of a future lesion. The method further includes inputting third images collected from a new patient to the processor to infer regions for future lesions, and displaying the inferred regions in a probability map at a display unit to indicate areas of increased likelihood of lesion occurrence.