Light Field Microscopy Denoising Decision via Cleanliness Scoring

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Solution Overview

Problem

Existing light field microscopy systems rely on subjective user judgment for determining whether to perform denoising, which is inefficient and affects the quality and accuracy of 3D reconstructed images due to noise.

Innovation Solution

A method for automatically determining denoising using a cleanliness score calculated from structural similarity index measures between multi-view rearranged images, comparing scores to a preset threshold, and performing denoising only when necessary.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If manual judgment is used to determine denoising needs, then the system operation is simple, but the efficiency is low and the determination is subjective

Engineering Contradiction:
Improvedenoising determination efficiencyVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system automatically evaluates image quality by calculating cleanliness scores based on structural similarity indices, eliminating the need for manual user judgment. The system serves itself by objectively determining whether denoising is required without human intervention.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces manual mechanical judgment with an automated computational system that uses image processing algorithms. The mechanical process of visual inspection is substituted with automated calculation of structural similarity indices and cleanliness scores.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If denoising is performed on all images, then image quality improves, but processing time and computational resources increase

Engineering Contradiction:
Improveimage qualityVSAvoidprocessing time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

Instead of applying denoising to all images uniformly, the system calculates cleanliness scores to identify only those images that actually require denoising. This partial action approach applies processing only where necessary, avoiding unnecessary computational time while maintaining image quality where needed.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The system performs a preliminary evaluation by calculating cleanliness scores before applying denoising. This preliminary action determines whether the denoising process is necessary, allowing the system to skip unnecessary processing steps and save time on images that are already of sufficient quality.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If subjective judgment is used for denoising determination, then the process is simple, but the accuracy and objectivity are reduced

Engineering Contradiction:
Improvedenoising determination accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system uses structural similarity indices to objectively measure image quality and provides feedback through cleanliness scores. This feedback mechanism gives quantitative, objective assessment of whether denoising is needed, replacing subjective judgment with measurable, repeatable criteria.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent transforms subjective visual judgment into objective parameter measurement by calculating structural similarity indices and cleanliness scores. These quantitative parameters provide precise, objective determination of image quality and denoising requirements, replacing ambiguous subjective assessment with measurable data.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12608775B2Method for automatically determining whether to perform denoising
Publication Date: 2026.04.21 ZHEJIANG HEHU TECH CO LTD
  • US12608775B2 patent drawing

AI summary

A method for automatically determining whether to perform denoising includes the following steps: S1: scanning a sample using a light field microscopy system to obtain a light field microscopic image containing 4-dimensional information, where the sample is a sample to be 3D reconstructed; S2: rearranging the light field microscopic image to obtain a multi-view rearranged image; S3: calculating a cleanliness score of the multi-view rearranged image; and determining whether to perform denoising process on the multi-view rearranged image, based on the cleanliness score of the multi-view rearranged image.