Integrated Light-Guiding Biochip Detection Device
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Solution Overview
Problem
Conventional biochip detection devices are bulky, expensive, and time-consuming due to their complex optical systems and point-by-point scanning methods, making them non-portable and costly for users.
Innovation Solution
A compact detection device integrating an image sensor with a light-guiding structure and a light source, featuring a light-guiding layer and guiding portions, which allows for simultaneous detection of specimens using an excitation beam and induced beams, reducing size, weight, and manufacturing costs while enhancing detection speed.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional optical elements and transport devices are used for biochip detection, then detection function is achieved, but device size and weight become large
Solution Approach 1:
The patent integrates the light source, light-guiding structure with guiding portions, image sensor, and carrier into a single unified detection device. This merging of previously separate components (optical system, detection system, and sample holder) eliminates the need for external transport devices and reduces overall device weight while maintaining full detection functionality.
Solution Approach 2:
The detection device is designed to perform multiple functions within a single compact unit: the light source provides excitation, the light-guiding structure directs light to multiple specimens simultaneously, and the image sensor detects induced beams from all specimens. This multi-functionality eliminates the need for separate transport and detection devices, significantly reducing weight.
2Reliability
If conventional optical elements and transport devices are used for biochip detection, then detection function is achieved, but manufacturing cost increases
Solution Approach 1:
By combining the light source, light-guiding structure, image sensor, and carrier into one integrated device, the patent eliminates the need for separate transport devices and complex optical assemblies. This integration simplifies the manufacturing process, reduces the number of components requiring assembly, and lowers overall manufacturing costs while maintaining detection functionality.
Solution Approach 2:
The light-guiding structure with guiding portions serves as an intermediary that efficiently directs light from a single light source to multiple specimens and routes induced beams to the image sensor. This intermediary structure replaces complex conventional optical systems with multiple separate elements, simplifying manufacturing and reducing costs.
3Measurement precision
If point-by-point scanning method is used for specimen detection, then detection accuracy is maintained, but detection time increases
Solution Approach 1:
The patent transitions from one-dimensional point-by-point scanning to two-dimensional parallel detection by arranging multiple guiding portions in an array that corresponds to the array of specimens. The image sensor captures induced beams from all specimens simultaneously across the entire biochip surface, maintaining detection accuracy while dramatically increasing detection speed.
Solution Approach 2:
The light-guiding structure is segmented into multiple guiding portions arranged in an array, with each guiding portion corresponding to a specific specimen location. This segmentation allows simultaneous detection of multiple specimens through parallel light paths, eliminating the sequential scanning process while maintaining the precision of individual specimen detection.
4Measurement precision
If conventional biochip detection device is designed with complete optical system, then detection accuracy is maintained, but device complexity increases
Solution Approach 1:
The light-guiding structure with guiding portions acts as an intermediary that simplifies the optical system by providing dedicated light paths from a single light source to multiple specimens and from specimens to the image sensor. This intermediary structure replaces the need for complex conventional optical systems with multiple separate light sources, mirrors, and lenses for each specimen, maintaining detection accuracy while reducing overall system complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The integrated design results in a portable, cost-effective detection device that significantly reduces detection time and manufacturing costs while maintaining accurate specimen analysis.
Implementation Method 1
The specimens emit induced beams when the specimens are irradiated by the excitation beam
Implementation Method 2
The excitation beam is transmitted to the specimens via the guiding portions. The induced beams are transmitted to the image sensor via the guiding portions and the light-guiding layer in sequence
Data Source
AI summary
A detection device for specimens includes an image sensor, a light-guiding structure, a carrier, and a light source. The light-guiding structure is disposed on the image sensor, and includes a light-guiding layer and a top layer. The light-guiding layer is disposed on the image sensor. The top layer is disposed on the light-guiding layer. The carrier is disposed on the light-guiding structure. The carrier has a number of wells arranged in an array located over the guiding portions. Each of the wells is configured to receive a specimen.