Lignin Fraction Antimicrobial Food Supplement Ingredient

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Solution Overview

Problem

The overuse and misuse of antibiotics in animal husbandry contribute to the antibiotic resistance crisis, and existing antimicrobial agents are often ineffective against various microorganisms, leading to environmental pollution and health risks.

Innovation Solution

The use of a lignin fraction as an anti-pathogenic agent in human and animal food supplements, which is effective against food pathogens without affecting probiotic microorganisms, thereby offering an alternative to antibiotics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If antibiotics are used to prevent and treat infections in animal husbandry, then the effectiveness against microorganisms is improved, but antibiotic resistance develops and environmental pollution increases

Engineering Contradiction:
Improveeffectiveness against microorganismsVSAvoidantibiotic resistance and environmental pollution
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters of the antimicrobial agent by using lignin with specific molecular weight (1,000-10,000 Da) and structural characteristics (specific phenolic hydroxyl groups and carbonyl groups). This parameter change allows the lignin to exhibit antimicrobial activity against pathogenic bacteria while being ineffective against probiotics, thus avoiding antibiotic resistance and environmental pollution issues associated with conventional antibiotics

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent extracts and utilizes specific functional groups from lignin (phenolic hydroxyl groups and carbonyl groups) that are responsible for antimicrobial activity. By focusing on these extracted functional components with specific molecular weight ranges, the invention achieves targeted antimicrobial effect without the harmful side effects of broad-spectrum antibiotics

Inventive Principle:
Principle #2Taking out (Extraction)

2Object-affected harmful factors

If known antimicrobial products are used to counteract bad microorganisms, then the protection against pathogens is improved, but effectiveness against many microorganisms is insufficient and multiple products are required

Engineering Contradiction:
Improveprotection against pathogensVSAvoideffectiveness against various microorganisms
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent demonstrates that lignin with the specified molecular weight range (1,000-10,000 Da) and structural characteristics exhibits broad-spectrum antimicrobial activity against multiple pathogenic bacteria including Salmonella, E. coli, and Listeria, while simultaneously being ineffective against probiotic bacteria. This single substance performs multiple antimicrobial functions that previously required multiple different products

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Object-affected harmful factors

If known antimicrobial products are used to prevent bacteria proliferation, then the hygiene maintenance is improved, but environmental pollution and product contamination occur

Engineering Contradiction:
Improvebacteria proliferation controlVSAvoidenvironmental pollution and product contamination
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent converts the previously underutilized lignin byproduct from the paper and pulp industry into a beneficial antimicrobial agent. By transforming this waste product into a functional ingredient with specific molecular weight characteristics, the invention achieves bacteria proliferation control while eliminating the environmental pollution associated with conventional antimicrobial products

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS12329725B2Use of a lignin fraction as a human and animal food supplement ingredient
Publication Date: 2025.06.17 UPM KYMMENE OYJ
  • US12329725B2 patent drawing
  • US12329725B2 patent drawing
  • US12329725B2 patent drawing

AI summary

The use of a lignin fraction as a human and animal food supplement ingredient, as well as food supplements comprising the same, are disclosed.