Organic Selenium Complex Salts from Lignin Hydrolysis
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Solution Overview
Problem
There is a need for a non-toxic, high bioavailability organic selenium source that can be administered in ultra-high doses to effectively treat diseases such as cardio-cerebrovascular diseases, liver diseases, and cancers, as conventional inorganic selenium is toxic and indigestible, and existing organic selenium formulations lack high selenium content and safety.
Innovation Solution
A method for preparing multivalent phenolic hydroxyl carboxylic acid selenium complex salts by hydrolyzing lignin to obtain polyphenolic compounds, reacting them with an inorganic metal base, and then with SeO2, resulting in an organic selenium composition with over 20% selenium content and low toxicity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If inorganic selenium is used as a supplement, then selenium content is high, but toxicity is high and bioavailability is low
Solution Approach 1:
The patent uses organic ligands (amino acids, phenolic compounds, or their derivatives) as intermediaries to bind with selenium, forming complex salts that serve as a bridge between inorganic selenium and biological systems. This intermediary structure reduces toxicity while maintaining high selenium content and improving bioavailability.
Solution Approach 2:
The invention creates composite materials by combining selenium with organic compounds (amino acids, phenolic compounds, carboxylic acids, or their derivatives) to form complex salts. This composite structure integrates the high selenium content of inorganic selenium with the low toxicity and high bioavailability of organic compounds.
2Object-affected harmful factors
If conventional organic selenium is used, then toxicity is reduced, but selenium content is low and dosage must be ultra high
Solution Approach 1:
The patent changes the chemical parameters of organic selenium by forming complex salts with specific organic ligands (amino acids, phenolic compounds, carboxylic acids). This parameter change increases the selenium content within the organic structure while maintaining low toxicity, eliminating the need for ultra-high dosages.
3Reliability
If existing organic selenium formulations are used, then safety is improved, but selenium content and effectiveness for serious diseases are insufficient
Solution Approach 1:
The patent creates a universal organic selenium complex salt platform that can be formed with multiple types of organic ligands (amino acids, phenolic compounds, carboxylic acids and their derivatives). This multi-functional approach maintains safety across different ligand choices while achieving high selenium content suitable for treating serious diseases.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The resulting multivalent phenolic hydroxyl carboxylic acid selenium complex salts exhibit revolutionary effects in killing bacteria, viruses, cancer cells, enhancing immunity, and removing oxygen free radicals, with no toxicity observed even at high doses, making them a safe and effective selenium supplement.
Implementation Method 1
hydrolyzing lignin to obtain multiple-structural polyphenolic compounds
Implementation Method 2
removing oxygen free radicals
Data Source
AI summary
A method for preparing selenium compounds, comprising following steps of: A. hydrolyzing lignin to obtain multiple-structural polyphenolic compounds; B. reacting the multiple-structural polyphenolic compounds with at least one kind of inorganic metal base to obtain multivalent phenolic hydroxyl carboxylate; and C. reacting the multivalent phenolic hydroxyl carboxylate with SeO2 to obtain multivalent phenolic hydroxyl carboxylic acid selenium complex salts, wherein the multivalent phenolic hydroxyl carboxylic acid selenium complex salts are organic selenium composition. The multivalent phenolic hydroxyl carboxylic acid selenium complex salts have characteristics of over 20% selenium content and no toxicity, and have revolutionary effects in killing bacteria, virus and cancer cell, enhancing human immunity, removing oxygen free radicals and etc.