Lipophilic Cannabinoid-Terpenoid Solution for Animal Therapy

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Solution Overview

Problem

Current cannabinoid-based treatments for animals lack standardization, leading to inconsistent and potentially toxic formulations, with a lack of clinical studies and acceptance within the veterinary medical community, particularly due to the toxicity of THC in dogs and the misunderstanding of CBD products for pets.

Innovation Solution

A lipophilic cannabinoid-terpenoid solution (CTS) comprising specific ratios of CBD, THC, and terpenes, administered via a controlled delivery system, providing a standardized and safe medication for treating various conditions in animals, including epilepsy, anxiety, and pain, while also collecting clinical data for dosage monitoring.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If CBD products for pets are provided only for oral administration, then the products are easy to manufacture and administer, but the absorption is inconsistent and poor

Engineering Contradiction:
Improveease of administrationVSAvoidabsorption consistency
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent introduces a lipophilic carrier as an intermediary substance that facilitates the absorption of cannabinoids through the blood-brain barrier. This carrier acts as a mediator between the cannabinoid and the target tissue, enabling consistent and reliable absorption while maintaining ease of oral administration. The lipophilic carrier solubilizes the cannabinoid and transports it across biological membranes, resolving the contradiction between ease of administration and absorption consistency.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If THC is used in cannabinoid products for animals, then the medicinal effects are enhanced, but the toxicity to animals especially dogs increases

Engineering Contradiction:
Improvemedicinal effectivenessVSAvoidtoxicity to animals
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by precisely controlling the concentration ratio of THC to CBD in the cannabinoid product. By adjusting this parameter (the ratio of THC to CBD), the formulation achieves optimal medicinal effectiveness while staying below toxic thresholds for animals. The lipophilic carrier further modifies the pharmacokinetic parameters, enabling enhanced efficacy at safer doses. This parameter optimization resolves the contradiction between medicinal effectiveness and toxicity.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If standardized cannabinoid-terpenoid solution is developed, then consistent and safe medication can be provided, but the development cost and complexity increase

Engineering Contradiction:
Improveconsistency and safetyVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent employs composite materials by combining multiple components in a standardized ratio: cannabinoids (CBD and THC), terpenoids, and a lipophilic carrier. This composite formulation achieves consistent and safe medication through the synergistic interaction of its components. The standardized composition of the composite material ensures reproducibility and reliability across batches, while the integrated nature of the composite reduces overall formulation complexity compared to separate preparations.

Inventive Principle:
Principle #40Composite materials

4Reliability

If clinical studies are conducted to provide reliable data, then acceptance within the medical establishment increases, but the time and resources required increase

Engineering Contradiction:
Improveclinical data reliabilityVSAvoidtime for clinical trials
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by conducting preclinical studies and establishing the foundational scientific rationale before initiating full clinical trials. The development of standardized formulations and preliminary safety data provides a solid basis that accelerates subsequent clinical testing. By preparing the groundwork in advance, the time required for full clinical validation is reduced, while still ensuring reliable and robust clinical data is obtained.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11759447B1Compound and method for treating diseases and disorders
Publication Date: 2023.09.19 DR ALEXANDER RASKIN CANCER RES INST LLC D B A RCR BIOPHARMA
  • US11759447B1 patent drawing
  • US11759447B1 patent drawing
  • US11759447B1 patent drawing

AI summary

Described is a cannabinoid-terpenoid solution (CTS) and method of treating a disease state or condition in animals other than humans via cannabinoid-terpenoid therapy. The CTS includes a unique combination of cannabinoids, terpenoids (terpenes), and a lipophilic carrier to allow safely and effectively treat the animal.