Liposomal Growth Factor Formulation for Skin Penetration Stability

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Solution Overview

Problem

Existing cosmetic preparations lack a combination of high purity plant growth factors, antioxidants, anti-wrinkle peptides, and stem cells encapsulated in liposomes for effective skin rejuvenation and repair.

Innovation Solution

A cosmetic product incorporating high purity plant growth factors, antioxidants, and anti-wrinkle peptides encapsulated in liposomes, along with stem cells, to enhance skin penetration and stability, using specific formulations for creams and serums.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If growth factors are incorporated into liposomes, then their penetration through skin and stability are improved, but the complexity of the formulation increases

Engineering Contradiction:
Improvestability of growth factorsVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent incorporates growth factors inside liposomes, which are themselves embedded within a cream or serum matrix. This nested structure protects the fragile growth factor proteins while maintaining their biological activity and skin penetration capability.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

Liposomes serve as an intermediary carrier between the growth factors and the skin. They facilitate the delivery of growth factors through the skin barrier while protecting the proteins from degradation, thus improving both stability and penetration.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If multiple active ingredients are combined in a single formulation, then the rejuvenation effect is enhanced, but the manufacturing precision requirements increase

Engineering Contradiction:
Improverejuvenation effectVSAvoidformulation precision
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent combines multiple active ingredients including growth factors, antioxidants, and peptides within a single unified formulation. The liposomal structure allows for the simultaneous incorporation of multiple components while maintaining their individual functionalities and synergistic effects.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The formulation uses composite liposomal structures that can accommodate multiple different molecular types (proteins, peptides, antioxidants) within a single delivery system, enabling enhanced rejuvenation effects while managing formulation complexity through standardized liposome preparation protocols.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Improves skin rejuvenation and repair by enhancing the penetration and stability of active ingredients, demonstrating improved cell proliferation, collagen synthesis, and anti-inflammatory effects.

Implementation Method 1

their penetration through the skin and their stability is improved while avoiding their degradation like proteins that they are

Methodology Applied
Scientific EffectLiposome penetration: Permeation

Data Source

PatentEP3162357B1Cosmetic product with liposomal growth factors
Publication Date: 2025.12.03 DERMOPARTNERS
  • EP3162357B1 patent drawingFigure 1~2
  • EP3162357B1 patent drawingFigure 3~4
  • EP3162357B1 patent drawingFigure 5~6

AI summary

Cosmetic product with liposomated growth factors with properties for repairing and rejuvenating the skin which include in the composition thereof high purity liposomated plant growth factors, liposomated antioxidants, liposomated anti-wrinkle peptides and stem cells in addition to other components for cosmetic use.