Liquid Administration Device with Force Inhibition Mechanism

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Solution Overview

Problem

Existing liquid administration devices, such as prefilled syringes, face challenges in administering high viscosity drugs and require significant force, making it difficult for individuals with limited dexterity or strength, and lack the ability to temporarily suspend drug administration.

Innovation Solution

A liquid administration device with a cylindrical body, needle tube, gasket, and a pressing mechanism that includes a pressing force transmission inhibiting mechanism, allowing for the inhibition of pressing force transmission to the gasket, enabling temporary suspension of drug administration and easy restart.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If a pressing operation is performed on a prefilled syringe to discharge high viscosity drug solution, then the drug solution can be administered, but the pressing resistance becomes high making it difficult to perform the pressing operation

Engineering Contradiction:
Improvedrug solution dischargeVSAvoidpressing resistance
Core Design Contradiction:
Quantity of substanceVSForce

Solution Approach 1:

A lever mechanism is introduced as an intermediary between the user's manual pressing force and the gasket. The lever amplifies the pressing force applied by the user, enabling effective discharge of high viscosity drug solutions without requiring excessive manual force. The lever acts as a mechanical mediator that transforms small input force into large output force on the gasket.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The manual pressing mechanism is replaced with an automated pressing mechanism that includes a lever, spring, and latch system. This mechanical substitution eliminates the need for users to directly apply high pressing force, especially benefiting individuals with limited strength or dexterity. The spring provides continuous pressing force while the lever amplifies it, and the latch mechanism controls the pressing action.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Ease of operation

If manual pressing is required to administer drug solution, then the device structure remains simple, but individuals with limited strength or dexterity cannot easily perform the pressing operation

Engineering Contradiction:
Improvepressing operation easeVSAvoiddevice structure
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

A lever mechanism is introduced as an intermediary between the user's manual pressing force and the gasket. The lever amplifies the pressing force applied by the user, enabling effective discharge of high viscosity drug solutions without requiring excessive manual force. The lever acts as a mechanical mediator that transforms small input force into large output force on the gasket.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The manual pressing mechanism is replaced with an automated pressing mechanism that includes a lever, spring, and latch system. This mechanical substitution eliminates the need for users to directly apply high pressing force, especially benefiting individuals with limited strength or dexterity. The spring provides continuous pressing force while the lever amplifies it, and the latch mechanism controls the pressing action.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Adaptability or versatility

If the pressing mechanism continuously presses the gasket to discharge drug solution, then the drug solution flows continuously, but it becomes impossible to temporarily suspend the administration

Engineering Contradiction:
Improveadministration control flexibilityVSAvoidmechanism structure
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The pressing mechanism incorporates a dynamic latch system that can switch between locked and unlocked states. The latch member can be positioned to engage with the lever, temporarily suspending the pressing action, or disengaged to allow continuous pressing. This dynamic capability enables flexible control over drug solution administration, allowing temporary suspension when needed while maintaining the ability to resume pressing by simply moving the latch.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables the prevention of wasteful or insufficient liquid discharge, allowing for controlled administration of drugs, even for users with limited strength, and facilitates easier handling of high viscosity drugs.

Implementation Method 1

a plunger that is interlocked with the gasket on a proximal side and discharges the drug solution through the opening part by pressing the gasket toward the distal direction

Methodology Applied
Scientific EffectElasticity: Elasticity

Implementation Method 2

U.S. Patent Publication No. 2011/0092915A discloses a liquid administration device which is constituted such that a plunger is pressed in a distal direction due to biasing force of a coil spring

Methodology Applied
Scientific EffectSpring force: Spring

Implementation Method 3

a pressing force transmission inhibiting mechanism configured to inhibit transmission of the pressing force to the gasket during the pressing operation

Methodology Applied
Scientific EffectMechanical constraint: Mechanical Force

Data Source

PatentUS10485929B2Liquid administration device
Publication Date: 2019.11.26 TERUMO KK
  • US10485929B2 patent drawing
  • US10485929B2 patent drawing
  • US10485929B2 patent drawing

AI summary

A liquid administration device includes: a structure that includes: a cylindrical body including a bottom part in a distal portion and an opening in a proximal portion, a needle tube positioned in the distal portion of the cylindrical body, the needle tube having a sharp needle tip at a distal end, wherein a proximal end of the needle tube is communicable with an inside of the cylindrical body, and a gasket installed in the cylindrical body, the gasket being slidable in an axial direction of the cylindrical body; an operation member configured to perform a pressing operation by pressing the gasket such that a liquid is discharged from the needle tube; a pressing mechanism configured to generate a pressing force for pressing the gasket; and a pressing force transmission inhibiting mechanism configured to inhibit transmission of the pressing force to the gasket during the pressing operation.