Liquid Composition Dye Stability via Cyclic Carbonate Esters

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Solution Overview

Problem

Liquid formulations containing dyes for agricultural chemicals are prone to instability against light and heat, leading to decomposition and adverse effects on efficacy, especially in the absence of solid protectants and without specific solvent selection for stability enhancement.

Innovation Solution

A liquid composition comprising a solvent with no nitrogen atom and a carbonyl group or sulfoxide compound, combined with non-cyclic alcohols, alkylene glycols, a physiologically active ingredient like neonicotinoid insecticides, water, and specific dyes, which enhances dye stability against light and heat.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a dye is added to a liquid formulation for easier discrimination and prevention of mis ingestion, then the formulation becomes more user-friendly, but the dye decomposes under light and heat leading to instability

Engineering Contradiction:
Improveease of discriminationVSAvoiddye stability
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The patent introduces a specific solvent system comprising cyclic carbonate esters (2.5-99.9999% by weight) as an intermediary medium that protects the dye from light and heat degradation. This solvent acts as a stabilizing matrix that maintains dye integrity while preserving its color properties for formulation identification.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical parameters of the formulation by selecting specific solvents (cyclic carbonate esters) and controlling their concentration ranges (2.5-99.9999% by weight). This parameter optimization ensures the dye remains stable under light and heat exposure while maintaining the liquid formulation's流动性 and color properties.

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If a liquid formulation is used instead of powdered formulation, then the formulation is easier to apply, but the dye has no solid substance to protect against light and decomposes more easily

Engineering Contradiction:
Improveease of applicationVSAvoidlight-induced decomposition
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The cyclic carbonate ester solvent serves as a protective intermediary that replaces the protective function normally provided by solid substances. It creates a stable liquid matrix that shields the dye from light penetration and degradation, enabling liquid formulations to maintain dye stability without requiring solid protectants.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a chemically inert liquid environment using cyclic carbonate esters that do not react with or promote dye degradation. This inert liquid atmosphere protects the dye from light-induced decomposition while maintaining the formulation's liquid state for easy application.

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

3Duration of action of stationary object

If the liquid formulation is kept at high temperature over a long period, then the formulation remains stable, but the dye decomposes by heat

Engineering Contradiction:
Improvestorage durationVSAvoiddye stability
Core Design Contradiction:
Duration of action of stationary objectVSStability of the object's composition

Solution Approach 1:

The patent optimizes the formulation parameters by selecting cyclic carbonate esters with specific boiling points and thermal stability characteristics. These solvents maintain formulation stability at high temperatures while creating a protective environment that prevents heat-induced dye decomposition during long-term storage.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The cyclic carbonate ester acts as a thermal intermediary that absorbs and dissipates heat energy without transferring it to the dye molecules in a way that causes decomposition. This protective medium allows the formulation to be stored at elevated temperatures for extended periods while preserving dye integrity.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Ease of manufacture

If no specific solvent is selected for stability enhancement, then the formulation is simpler to prepare, but the dye lacks protection against light and heat

Engineering Contradiction:
Improveformulation simplicityVSAvoiddye stability
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent establishes specific concentration parameters for cyclic carbonate esters (2.5-99.9999% by weight) that optimize both manufacturing simplicity and dye stability. This parameter-based approach provides clear formulation guidelines that maintain reliability without overly complicating the manufacturing process.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves excellent dye stability and uniform color development over time, ensuring the efficacy of the ectoparasite controlling agent for mammals and avians without phase separation or skin irritation.

Implementation Method 1

a liquid composition containing (a) a solvent having no nitrogen atom and either having a carbonyl group in the molecule or being a sulfoxide compound

Methodology Applied
Scientific EffectSolvation: Solvation

Data Source

PatentEP2014163B1Liquid composition, process for production of the liquid composition, and ectoparasite controlling agent for use in mammals and avians
Publication Date: 2016.09.28 NIPPON SODA CO LTD
  • EP2014163B1 patent drawingFigure 1(a)~1(f)
  • EP2014163B1 patent drawingFigure 2

AI summary

A liquid composition comprising (a) 21 to 70 parts by weight of a solvent having no nitrogen atom and having a carbonyl or sulfonyl group in the molecule, (b) 30 to 78.9 parts by weight of at least one component selected from the group consisting of a non-cyclic alcohol, an alkylene glycol, a polyalkylene glycol, a triol, a glycol monoacetate and a glycol monoalkyl ether, (c) 0.001 to 30 parts by weight of a physiologically active ingredient, and (d) 0.001 to 49 parts by weight of water.