High-Solids Liquid Lysine Composition That Resists Crystallization
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing liquid lysine products in free base form crystallize at concentrations above 50% due to limited solubility, requiring heated storage and transportation, and there is a need for more concentrated liquid lysine formulations to enhance nutritional benefits in feed products.
Innovation Solution
Incorporating lecithin-based additives, such as crude filtered lecithin, fluid lecithin, or chemically modified lecithin, to inhibit crystal formation or precipitation in liquid compositions, allowing concentrations of lysine up to 80% by weight, along with optional use of co-emulsifiers and suspending agents like water-soluble polymers.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If the concentration of liquid lysine in free base form is increased above 50%, then the nutritional benefits and functional value are enhanced, but crystal formation occurs due to limited solubility
Solution Approach 1:
The patent introduces water-soluble polymers as intermediary substances that interact with lysine molecules to prevent crystal formation. These polymers act as mediators between the high concentration lysine and the aqueous environment, maintaining solubility and preventing precipitation through molecular interaction and steric hindrance mechanisms.
Solution Approach 2:
The patent changes the physical-chemical parameters of the lysine solution by adding water-soluble polymers, which alter the solubility characteristics and crystallization behavior of lysine. This parameter change allows the system to maintain higher lysine concentrations without reaching the crystallization point, effectively shifting the phase behavior of the solution.
2Quantity of substance
If the concentration of liquid lysine in free base form is increased above 50%, then the functional value is increased, but heated storage and transportation facilities are required
Solution Approach 1:
Water-soluble polymers serve as protective intermediaries that stabilize lysine in high concentration formulations across a broader temperature range. These polymers prevent temperature-induced crystallization by maintaining molecular dispersion and reducing the tendency of lysine to precipitate during storage and transportation temperature fluctuations.
Solution Approach 2:
The addition of water-soluble polymers changes the thermal stability parameters of the lysine solution, raising the temperature range over which the solution remains stable and liquid. This parameter modification eliminates the need for heated storage facilities by extending the liquid stability range to include ambient and lower temperatures.
3Quantity of substance
If liquid lysine concentration is increased to enhance nutritional benefits, then the efficacy in feed formulations is improved, but handling and transportation become more difficult due to solidification
Solution Approach 1:
Water-soluble polymers act as operational intermediaries that maintain the fluidity and handleability of high-concentration lysine formulations. These polymers prevent solidification during handling and transportation by continuously stabilizing the lysine in solution, allowing the product to be pumped, mixed, and processed like conventional liquid feed additives despite the high active ingredient concentration.
Solution Approach 2:
The patent modifies the rheological and phase behavior parameters of the lysine solution through polymer addition, changing it from a system that solidifies at high concentrations to one that maintains liquid flow properties. This parameter change enables easy handling and transportation of ultra-concentrated lysine products without requiring special equipment or procedures.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution maintains the liquid state of lysine at higher concentrations, facilitating easier handling and transportation while enhancing the functional value and nutritional efficacy of feed formulations.
Implementation Method 1
Incorporating lecithin-based additives, such as crude filtered lecithin, fluid lecithin, or chemically modified lecithin, to inhibit crystal formation or precipitation in liquid compositions
Implementation Method 2
Lecithin is an emulsifier and a surface active agent... Emulsifiers are amphiphilic molecules that carry a hydrophilic head and a hydrophobic tail
Implementation Method 3
The liquid composition may further include a suspending agent, such as a water soluble polymer
Data Source
AI summary
The present invention discloses liquid compositions that include an active compound, water, and means for inhibiting crystal formation or precipitation of the active compound in the liquid composition.