Liquid Sample Collector Interface with High-Capacity Cylindrical Filter
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Solution Overview
Problem
Existing liquid sample collector interfaces, such as cannulas, suffer from small capacity filters that clog prematurely, require tool-based filter removal, and are unable to withstand high backwashing pressures, which are limitations in dissolution testing for pharmaceuticals.
Innovation Solution
A liquid sample collector interface with a cap and housing design that accommodates a high-capacity filter with a large surface area, allowing for easy tool-free filter removal and withstanding high back pressures during backwashing, featuring interlocking grooves and protuberances for secure coupling and an O-ring seal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If a small capacity disc filter is used in the cannula, then the device structure remains simple, but the filter clogs prematurely after passing only a small sample volume
Solution Approach 1:
The filter is changed from a disc shape (2D surface) to a cylindrical shape (3D volume), increasing the filtering surface area from a flat disc to the lateral surface of a cylinder. This dimensional change allows significantly higher filter capacity without proportionally increasing the footprint or complexity of the filter chamber structure.
2Ease of operation
If the filter is installed flush with the end of the cap, then the housing structure remains simple, but the filter requires a tool for removal
Solution Approach 1:
The filter is designed to extend beyond the cap end before installation, allowing the user to grasp and remove it manually. This preliminary positioning of the filter protruding from the cap eliminates the need for tools during filter removal while adding minimal structural complexity to the cap design.
3Strength
If the cap is retained by a friction fit O-ring, then the assembly is simple, but the cap cannot withstand high back pressures during backwashing
Solution Approach 1:
The cap-housing coupling is divided into multiple engagement points through grooves and protuberances, distributing the backpressure load across several locations rather than relying on a single friction fit. This segmentation provides mechanical strength to withstand high backwashing pressures while maintaining a relatively simple overall structure.
4Quantity of substance
If the filter is positioned to prevent blocking the aperture, then the housing structure remains simple, but the filter surface area is limited
Solution Approach 1:
The filter transitions from a disc shape to a cylindrical shape, utilizing the lateral surface area of the cylinder for filtration. This allows the filter to extend axially beyond the cap while maintaining a compact radial footprint, increasing filter surface area without complicating the housing interior structure.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The design prevents premature filter clogging and ensures reliable operation under high backwashing pressures, extending filter life and improving sampling efficiency in dissolution testing.
Implementation Method 1
an O-ring seal to prevent leakage under high back pressure
Implementation Method 2
a filter with a large surface area that extends beyond an end of the filter chamber
Data Source
AI summary
Liquid sample collector interface, comprising a cap detachably interlocked with housing, with the cap having a filter chamber that accommodates a filter with a large surface area that extends beyond an end of the filter chamber for easy removal of the filter without the use of tools.