List Mode Image Reconstruction With Subset Balance Correction

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Solution Overview

Problem

Conventional list mode image reconstruction methods struggle to generate a quantitative radioactivity distribution image due to uneven number of events between subsets, leading to non-convergence of calculated values and pixel value changes depending on the subset number.

Innovation Solution

The method involves dividing list mode data into subsets, acquiring subset balance coefficients based on the number of events, and adjusting back projection values using these coefficients to update the radioactivity distribution image.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If list mode data is divided into subsets for iterative calculation, then calculation speed is improved, but the calculated value does not converge to the correct radioactive concentration due to uneven event distribution

Engineering Contradiction:
Improvecalculation speedVSAvoidradioactive concentration accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent introduces subset balance coefficients as a correction parameter that compensates for uneven event distribution across subsets. By calculating the ratio of total events to subset events and applying this coefficient during iterative reconstruction, the method maintains both parallel processing speed and quantitative accuracy of radioactive concentration measurement.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If the number of subsets is increased to improve calculation efficiency, then processing speed increases, but pixel values change depending on the subset number making quantitative analysis difficult

Engineering Contradiction:
Improveprocessing speedVSAvoidpixel value consistency
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent employs a feedback mechanism where subset balance coefficients are calculated based on the actual event distribution in each subset and applied to correct the reconstructed image. This feedback loop ensures that regardless of the number of subsets used, the final pixel values converge to the correct radioactive concentration, providing stability and reproducibility.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12394118B2List mode image reconstruction method and nuclear medicine diagnostic apparatus
Publication Date: 2025.08.19 SHIMADZU CORP
  • US12394118B2 patent drawing
  • US12394118B2 patent drawing
  • US12394118B2 patent drawing

AI summary

A list mode image reconstruction method includes a step of dividing list mode data into a plurality of subsets and a step of acquiring a subset balance coefficient based on the number of events in the plurality of subsets.