Liver Segmentation in MR Images Using Multi-Channel Features

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Solution Overview

Problem

Manual segmentation of the liver in magnetic resonance images is challenging due to variability in intensity units across scans, making global intensity cues unreliable for organ segmentation.

Innovation Solution

A method for fully automatic segmentation using a discriminative learning-based framework that utilizes multi-channel features from MRI images, employing statistical classifiers and a training database of liver shapes to establish relationships between features from multiple channels and the liver boundary, with Marginal Space Learning for pose estimation and fine-scale boundary localization.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual delineation of the liver is performed, then segmentation can be achieved, but it is time-consuming and shows significant variability among users

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidtime-consuming task
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs automatic liver segmentation without human intervention by using training databases and statistical classifiers to autonomously identify and delineate liver boundaries in MR images, eliminating the need for manual user input while maintaining consistent segmentation quality

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the manual mechanical process of user-based delineation with an automated computational system using training databases, feature extraction, and statistical classifiers to perform segmentation objectively and consistently

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Ease of operation

If global intensity cues are used for segmentation in MR images, then segmentation can be simplified, but intensity units vary across scans making them unreliable

Engineering Contradiction:
Improvesegmentation simplicityVSAvoidintensity cue reliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent divides the segmentation process into multiple independent stages: initial boundary detection using training databases, pose estimation, and fine-scale boundary localization. Each stage uses specific features appropriate to that stage rather than relying on a single global intensity measure

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system transforms the segmentation approach by changing from relying on absolute intensity values to using relative intensity relationships and multi-channel feature combinations, which are invariant to the varying intensity units across different MR scans

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If single-channel MR images are used for segmentation, then processing is simpler, but segmentation accuracy is reduced

Engineering Contradiction:
Improveprocessing complexityVSAvoidsegmentation accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent combines information from multiple MR image channels by extracting features from each channel and integrating them through statistical classifiers, allowing the system to leverage the complementary information in each channel to improve overall segmentation accuracy

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS9367924B2Method and system for segmentation of the liver in magnetic resonance images using multi-channel features
Publication Date: 2016.06.14 SIEMENS HEALTHINEERS AG
  • US9367924B2 patent drawing
  • US9367924B2 patent drawing
  • US9367924B2 patent drawing

AI summary

A method and system for fully automatic liver segmentation in a multi-channel magnetic resonance (MR) image is disclosed. An initial liver boundary in the multi-channel MR image, such as an MR Dixon scan. The segmented initial liver boundary in the multi-channel MR image is refined based on features extracted from multiple channels of the multi-channel MR image using a trained boundary detector. The features may be extracted from an opposed channel and a water channel of an MR Dixon scan.