Loopless MRI Probe Inverting Coordinate System for Vascular Imaging

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Solution Overview

Problem

Conventional MRI methods struggle with low anatomic resolution and signal-to-noise ratio when imaging vascular walls, particularly due to the image frame being locked to the scanner coordinate system, which limits real-time imaging and increases RF power deposition.

Innovation Solution

The development of a loopless MRI antenna probe that locks its frame of reference to the probe itself, allowing for real-time imaging and reducing RF excitation to a small volume, thereby enhancing signal-to-noise ratio and improving imaging efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional MRI methods are used with scanner-locked coordinate system, then imaging coverage is comprehensive, but anatomic resolution and signal-to-noise ratio are low

Engineering Contradiction:
Improveanatomic resolutionVSAvoidcoordinate system locking
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Instead of locking the image frame to the scanner coordinate system, the patent inverts the approach by locking the coordinate system to the probe. The probe becomes the fixed reference point, and images are acquired as the scanner moves relative to the probe, thereby achieving high anatomic resolution at the probe location while maintaining comprehensive coverage through probe positioning.

Inventive Principle:
Principle #13The other way round (Inversion)

Solution Approach 2:

The patent applies local quality by concentrating imaging resources on the local region around the probe. By making the probe the fixed reference point, the system achieves superior anatomic resolution and signal-to-noise ratio in the immediate vicinity of the probe (local region), while still providing broader anatomical context through coordinated probe movement and scanning.

Inventive Principle:
Principle #3Local quality

2Productivity

If scanner coordinate system is used, then imaging stability is maintained, but real-time imaging capability is limited

Engineering Contradiction:
Improvereal-time imaging speedVSAvoidcoordinate system stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent inverts the traditional MRI coordinate system approach by making the probe the fixed reference frame instead of the scanner. This allows the scanner to move relative to the probe, enabling real-time imaging as the scanner rapidly acquires data from different positions while the probe remains stationary, thereby improving imaging speed without sacrificing coordinate stability.

Inventive Principle:
Principle #13The other way round (Inversion)

Solution Approach 2:

The system incorporates feedback mechanisms to track probe position and orientation in real-time, adjusting the coordinate transformation dynamically. This feedback loop ensures that even as the scanner moves for rapid imaging, the coordinate system remains stable and accurately reflects the probe's location, maintaining both real-time capability and coordinate stability.

Inventive Principle:
Principle #23Feedback

3Area of stationary object

If full-volume RF excitation is applied, then complete anatomical coverage is achieved, but RF power deposition increases

Engineering Contradiction:
Improveimaging coverage areaVSAvoidRF power deposition
Core Design Contradiction:
Area of stationary objectVSUse of energy by moving object

Solution Approach 1:

The patent applies local quality by concentrating RF excitation energy in the immediate vicinity of the probe rather than distributing it throughout the entire imaging volume. The probe acts as a localized RF source, providing sufficient excitation for high-resolution imaging of the local region while minimizing RF power deposition in distant tissues, thereby reducing overall energy consumption and improving safety.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The imaging volume is segmented into multiple regions, with the probe serving as a movable local excitation source. Instead of exciting the entire volume simultaneously with high power, the system segments the imaging task into sequential local acquisitions as the probe moves through different positions, achieving complete anatomical coverage through cumulative local imaging while keeping RF power deposition at each location low and manageable.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables high-resolution, real-time imaging of vascular structures with reduced RF power deposition, improving the accuracy and efficiency of MRI-guided interventions and diagnostics.

Implementation Method 1

providing bursts of radio frequency (RF) energy on a specimen positioned within a main magnetic field in order to induce responsive emission of magnetic radiation from the hydrogen nuclei or other nuclei

Methodology Applied
Scientific EffectElectromagnetic radiation: Electromagnetic Induction

Implementation Method 2

a specimen positioned within a main magnetic field

Methodology Applied
Scientific EffectMagnetic field: Magnetic Field

Implementation Method 3

induce responsive emission of magnetic radiation from the hydrogen nuclei or other nuclei

Methodology Applied
Scientific EffectMagnetic resonance: Electromagnetic Induction

Data Source

PatentEP2111158B1Methods for local endoscopic MRI
Publication Date: 2020.09.09 JOHNS HOPKINS UNIVERSITY
  • EP2111158B1 patent drawingFigure 1
  • EP2111158B1 patent drawingFigure 2~3(c)
  • EP2111158B1 patent drawingFigure 3(a)

AI summary

Featured are a device with localized sensitivity to magnetic resonance signals, an imaging system using such a device and MRI methods for performing internal MRI or MRI Endoscopy. Such an MRI method includes introducing an MRI antenna or probe into the specimen to be imaged, the antenna being configured in accordance with the devices described herein, so that the spatial coordinate frame of imaging is inherently locked or defined with respect to the introduced antenna thereby providing imaging of the specimen from the point of view of the antenna. Further such imaging is conducted so that the MRI signal is confined substantially to a volume with respect to a particular region of the antenna or probe.